Vol 15, No 5-6 (2015)
- Year: 2015
- Articles: 87
- URL: https://ogarev-online.ru/2410-3764/issue/view/1371
- DOI: https://doi.org/10.17816/2072-2354.2015.0.5-6
Articles
TREATMENT AND PREVENTION OF CERVICAL DYSPLASIA IN WOMEN LIVING IN THE ENVIRONMENTALLY POLLUTED AREA OF THE CITY
Abstract
The results of conservative and surgical treatment of patients diagnosed with dysplastic diseases of ectocervix, living in the environmentally polluted area of the city and in the region with more favorable environmental conditions, were examined. The conclusions on the effectiveness of various methods and the need to implement the prevention programs for cervical dysplasia were drawn. The detection of abnormality of enzyme activity and content of chemicals in the cell, observed in the absence of clinical manifestation of the disease, will allow correcting the pathological conditions in the subclinical stage.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):7-9
7-9
HYPERPLASTIC DISEASES OF ENDOMETRIUMIN PATIENTS LIVING IN UNFAVOURABLE ECOLOGICAL CONDITIONS
Abstract
Comparison of the groups of patients living in conditions of ecological trouble and more favorable environmental conditions shows that long-term exposure of the woman’s organism to the harmful impurity of air decreases its adaptive capabilities. This leads to the development of the reproductive system diseases. Based on the research and analysis of the results of therapy of endometrium hyperplastic diseases, the author formulates the priority directions of endometrium diseases prevention programs for residents of the polluted areas.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):10-13
10-13
OBESITY IS AN INDEPENDENT RISK FACTOR FOR DEVELOPMENTOF GESTATIONAL COMPLICATIONS
Abstract
The main goal of this research was to evaluate if there is an impact of obesity on pregnancy outcomes, particularly on weight of newborn infants. 308 delivery cases were reviewed, followed by investigation of placental histology after deliveries in women with normal weight, increased body mass index and obesity. We compared placenta’s morphology findings, biochemical blood parameters and risks for hyportrophic infants born in preterm and normal deliveries of women with different body mass indices. This study shows that obesity increases the risk of hypotrophy of newborn in preterm deliveries on 28-36 weeks of gestation by 4,4, but the highest level (by 6) was noted on 28-32 weeks of gestation, and only 3,4 on 33-36 weeks of gestation.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):14-20
14-20
OPTIMIZATION OF MANAGEMENT OF PREGNANT WOMEN WITH EARLY TOXICOSIS BY SELECTION OF PREDICTORS OF COMPLICATED GESTATION COURSE
Abstract
The aim of the present study was selection of pathogenetically substantiated informative predictors of severe early toxicosis. Quantitative objectification of markers of embryo(feto)placental dysfunction and metabolic disorders was conducted in 172 pregnant women with early toxicosis of varying severity in the course of a prospective study. Clinical diagnostic parallels allowed us to determine the predictive value of diagnostic tests in relation to the development of severe toxemia (blood levels of leptin, fasting glucose, FER, L CD95+, total IgE, CRP, and TNF-a, the maximum amplitude of platelet aggregation, fibronectin). Active implementation of predictors of severe early toxicosis will allow timely prevention of this complication and complications of the second half of pregnancy.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):21-27
21-27
28-32
33-37
CLINICAL AND MICROBIOLOGICAL CHARACTERISTICSOF CERVICAL DYSPLASIA
Abstract
The nature of vaginal fluid and its microbiocenosis in residents of environmentally disadvantaged areas and areas with more favorable environmental conditions was examined for the purpose of determining the role of microbial factors in the etiology and pathogenesis of ectocervix dysplasia. The study showed that the cervical dysplasia causes a significant abnormality of the microecological system, especially noticeable in women from the main group, which is reflected in a significant increase in the number of different species of microorganisms with a predominance of strict anaerobic bacteria. A direct moderate correlation between duration of patients’ habitation in environmentally disadvantaged areas and the growth of microbial and fungal flora in smears was found.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):38-40
38-40
COMPARATIVE ANALYSES OF DIAGNOSTIC METHODS OF EARLY HYPOGALACTIA USING TESTS OF CLINICAL EPIDEMIOLOGY
Abstract
The article is devoted to assessing the diagnostic value of different methods of diagnosing early hypogalactia to select the most informative and correct this pathology in time. In the study, detection of early hypogalactia was conducted in 200 pregnant women with risk factors for developing this disease with the help of diagnostic tests, including crystallographic method. The study assessed the clinical effectiveness of the method of diagnosis of early hypogalactia, determining the qualitative composition of the mammary glands and secretion of prolactin levels in blood serum, the thermometric method, the method using a 15% soap solution, smear morphotypes of secretion of the mammary glands, crystallographic method. To calculate the sensitivity, specificity, positive predictive value and negative results, the diagnostic accuracy of diagnostic methods for early disorders of lactation function, the daily amount of milk on the 4, 5, 6 days of post-partum period was counted retrospectively, which revealed, taking into account the needs of a newborn, the presence or absence of early hypogalactia. The study showed that the crystallographic method of diagnosing early hypogalactia has the greatest diagnostic significance (87.9% Se, Sp 88.3%, P 88.0%), compared to other studied methods.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):41-47
41-47
INFORMATIVE PREDICTORS OF MAJOR OBSTETRICAL SYNDROMES IN PREGNANT WOMEN WITH EMBRYPLACENTAL DYSFUNCTION
Abstract
The article evaluates the prognostic significance of the predictor indices that reflect the state of the major biological systems involved in the formation of the embryo(feto)placental disorders and major obstetrical syndromes. As a result of the conducted study of predicting major obstetrical syndromes (PN, PE, PERP, ETC) using tests of clinical epidemiology - the sensitivity, specificity, predictive values of positive and negative results, diagnostic accuracy, the informative predictor indices were selected (PI= FER/TNF x 100; PI= PAMG/FER x 100; PI= L CD95+/PSF x 100), reflecting the degree of impairment of various compensatory and protective-adaptive processes in FPC and system dysfunction. High prognostic value of the proposed predictor index can be recommended for widespread practical use.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):48-55
48-55
THE RISK FACTORS FOR FUNCTIONAL DISORDERS ASSOCIATED WITH ABDOMINAL PAIN IN ADOLESCENTS
Abstract
Etiopathogenetic aspects of functional disorders of the gastrointestinal tract (GI FD) manifested in abdominal pain in adolescents are under-investigated, and currently there are certain problems in treatment of these conditions. At the present stage, biopsychosocial model of GI FD seems to be the most reasonable. From this perspective, we found that the leading factors of formation of the GI FD in these age groups are mainly psychosocial factors.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):56-59
56-59
TEN-YEAR DYNAMICS OF BIOLOGICAL RISK FACTORS IN TODDLERS WITH IRON DEFICIENCY ANEMIA AND THEIR HEALTHY PEERS
Abstract
Iron deficiency anemia has a significant negative impact on various aspects of children’s health. Wide variety of risk factors and com plicity of risk groups are hampering the timely prevention of the disease. The aim of the study was the assessment of the dynamics of known risk factors of iron deficiency anemia in toddlers. A retrospective study of known risk factors frequency in 184 children born in the period from 01.07.1998 to 31.06.1999 (101 with iron deficiency anemia and 83 healthy) and 228 children born in the period from 01.07.2008 to 31.06.2009 (135 with iron deficiency anemia and 93 healthy) was held. We found the change of significance of most antenatal risk factors. Mother’s chronic pathology of gastrointestinal tract and atopic diseases are significant risk factors of IDA. We found increased impact of mother’s endocrine disease on the development of IDA in toddlers. Antenatal risk factors that directly disrupt placental transportation of iron from mother to the fetus such as premature birth and placenta pathology also became more important. Low birth weight (more than -3SD) and length at birth less then median (more than -1SD) are risk factors of IDA. The duration of breast-feeding for more than 9 months of life is a new risk factor of IDA in toddlers.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):60-65
60-65
ESTIMATION OF THE MORPHO-FUNCTIONAL STATE OF THE MYOCARDIUM IN CHILDREN WITH PREMATURE BEATS
Abstract
The article presents information on the structural changes of the heart in children with ventricular and supraventricular premature beats. Statistical processing using contingency tables and the calculation of χ2 allowed determination of significant differences between the values. Analysis of the main indicators of the morpho-functional state of the myocardium in patients with ventricular and supraventricular premature beats made it possible to identify the most adverse changes in the structure of the heart and blood vessels.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):66-69
66-69
SOCIAL FACTORS DYNAMICS IN CHILDREN WITH EARLY ONSETOF IRON DEFICIENCY ANEMIA AND THEIR HEALTHY PEERS
Abstract
The frequency of iron deficiency and iron deficiency anemia (IDA) remains high in the pediatric population, but due to possible adverse effects of iron supplementation, routine prophylaxis is limited. In this regard, it is important to detect risk groups of iron deficiency anemia. After exclusion of antenatal risk factors, one of the most significant risk factors is the low socioeconomic level. The aim of the study was the assessment of IDA socio-economic risk factors dynamics. A retrospective study of known socio-economical risk factors frequency in 184 children born in the period from 01.07.1998 to 31.06.1999 (101 with iron deficiency anemia and 83 healthy) and 228 children born in the period from 01.07.2008 to 31.06.2009 (135 with iron deficiency anemia and 93 healthy) was held. Socio-economic factors in modern conditions have little effect on IDA in toddlers. Protective effect against IDA has mother’s status of a housewife. At the greatest risk of IDA are toddlers who are brought up in large families (3 children or more).
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):70-74
70-74
CORRELATION OF POSITIVE FAMILY HISTORY OF ALLERGIC DISEASES IN INFANTS AND THE NATURE OF THEIR FEEDING AT THE FIRST YEAR OF LIFE
Abstract
The aim of our study was to identify frequency of positive family history of allergic diseases in infants and its impact on the nature of their feeding at the first year of life. After analyzing the results of parents’ survey of 1030 young children, we have identified positive family history of allergic diseases in 294 babies (28.5%). The character of their feeding had little difference from the feeding of infants without any allergic family history, which does not meet the current recommendations for the prevention of allergic diseases in children at risk.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):75-79
75-79
PROGNOSTIC VALUE OF DIFFERENTTREATMENT METHODS FOR BLADDER CANCER
Abstract
The study of the prognostic value of different methods in the treatment of bladder cancer was carried out, covering approaches to the treatment of bladder cancer. A review of Russian and foreign sources of literature on the treatment of bladder cancer and predicting outcomes was performed, including the study of articles and papers on the problems of this disease.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):80-85
80-85
ANALYSIS OF QUALITY OF LIFE OF PATIENTS WITH COLOSTOMY
Abstract
This article is dedicated to the issue of quality of life of patients with colostomy who were operated on for complicated colorectal cancer. Quality of life after resection of obstructive colon has been studied using a scale FACT-C, which consisted of the sum of the values of the scale FACT-G and a special module for colorectal cancer CRC - colorectal cancer concerns. The comparative analysis of the quality of life after operation was performed for each module scales FACT-G, a special module CRC and the total scale value FACT-G, FACT-C and TOI. The study concluded that the dynamics totals FACT-G, FACT-C, TOI and additional questions show the improving quality of life of patients with colostomy. Colostomy was formed in obstructive colon resection using the technique of sphincter modeling by the proposed method.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):86-91
86-91
CYTOREDUCTIVE TREATMENT OF PATIENTS WITH MULTIPLE BILOBAR COLORECTAL CANCER METASTASES IN THE LIVER WITH THE USE OF RADIOFREQUENCY THERMAL ABLATION
Abstract
This study presents the results of the treatment of 168 patients with the diagnosis of colorectal cancer stage 4 with bilobar liver metastases. In the control group (78 patients), cytoreductive surgery was carried out with atypical liver resection. In the study group (90 patients), removal of the tumor was followed by radiofrequency thermal ablation of liver metastases.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):92-95
92-95
ADVANTAGES OF CT-FLUOROSCOPY AS A METHOD TO CONTROLTHE POSITION OF THE ELECTRODE AT RADIOFREQUENCY ABLATION OF LUNG TUMORS
Abstract
From 2008 to 2012 in the Samara Regional Clinical Oncology Center radiofrequency thermoablation (RFA), using different guidance systems, has been performed on 306 lesions in 221 patients with primary and metastatic lung tumors. 22 (7.2%) were completed under the fluoroscopy, 31 (10.1%) under the control of computed tomography (CT), 65 (21.2%) were guided by combinations of CT and fluoroscopy, 147 (48.1%) with CT-fluoroscopy guidance, 19 (6.2%) under the cone-beam CT and 22 (7.2%) under ultrasound control. We have found that CT-fluoroscopy is the best guidance system for lung minimally invasive interventions.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):96-101
96-101
AETIOPATHOGENESIS OF BLADDER CANCER AND FORECASTING THE PROBABILITY OF DISEASE
Abstract
The study of aethiopathogenesis of bladder cancer and the prognosis of the disease occurrence, as well as the possibility of prevention is presented in the article. The review of Russian and foreign literature sources, considering the development of bladder cancer incidence and prognosis was carried out. Forecasting the development of malignancies is currently a priority in terms of modern oncology.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):102-107
102-107
DYNAMICS OF INDICATORS OF HOMEOSTASIS, METABOLISM, HORMONAL, IMMUNE, CARDIAC STATUS OF PATIENTS WITH THYROID CANCER IN PRE- AND POSTOPERATIVE PERIODS
Abstract
As a result of studies the authors identified that 65 patients (who had differentiated thyroid cancer T1-3 N0-1 M0) had multiple hormonal changes, disorders of homeostasis and metabolism, disruption of antioxidant processes of cellular and humoral immunity, of cardiovascular system in the preoperative period and in the early postoperative period. In the recovery period there was no positive trend for the majority of investigated parameters: they marked persistent destabilization of the myocardium with increased frequency and increased graduation of ventricular arrhythmia, indicators of psycho-emotional condition deteriorated. Thus, hormone therapy in combination with traditional cardiotherapy does not solve all the problems of disadaptation, which requires further search for new science-based methods of complex rehabilitation of patients with thyroid cancer.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):108-116
108-116
EFFECT OF INTRAOPERATIVE ULTRASONOGRAPHY ON SUCCESS AND DURATION OF THORACOSCOPIC RESECTIONS
Abstract
The aim of this study is to explore the possibilities of intraoperative ultrasonography (IOUS) in patients with VATS resections of lung lesions. The article presents practical results of this imaging technique in 391 patients who were treated from 2011 to 2014. The effectiveness of IOUS is compared with classical methods of searching intraparenchymal lesions with subsequent video-assisted thoracic surgery (VATS).
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):117-123
117-123
COMPARATIVE ANALISIS OF SURGICAL TREATMENT OF CHILDREN WITH CONGENITAL OBSTRUCTIVE MEGALOURETER
Abstract
The paper presents the evaluation of results of surgical treatment of children with congenital obstructive megaloureter in the Department of pediatric urology of Samara regional clinical hospital named after V. D. Seredavin. The most complete restoration of anatomy and function of the urinary tract was achieved in children who underwent drainage of the urinary tract on the affected side and correction of bladder dysfunction. According to our results, intravesical transplantation of the ureter gives better results compared to extravesical transplantation, due to the technical ability to meet the required ratio of the ureter’s diameter to the length of the submucosal tunnel during the transplantation.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):124-126
124-126
DIAGNOSIS OF INCONSISTENCY OF FUNDOPLICATION CUFF IN PATIENTS UNDERGOING CORRECTION OF HIATAL HERNIA
127-129
OSTEOSYNTHESIS AT RIB FRACTURES:THE ASPECTS OF SURGICAL TECHNIQUE
Abstract
The article describes modern aspects of surgical treatment of patients with multiple rib fractures and flail chest. The main method of treatment at these patients was rib osteosynthesis. The comparison between different kinds of surgical approaches was carried out. In addition, the basic criteria and conditions for every approach were specified. The advantages and disadvantages of surgical accesses were marked. We described some methods of improvement of the technique and optimization of the approaches. The necessity for performing thoracoscopy in order to eliminate intrathoracic injuries was indicated.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):130-133
130-133
CLINICAL ALGORITHM FOR THE DIAGNOSIS AND TREATMENTOF PORTAL VEIN THROMBOSIS
Abstract
The article is devoted to modern concepts of pathogenesis, clinic, treatment strategies for thrombosis of the trunk and main branches of the portal vein. The article presents developed in the clinic tactics algorithms for the progression of bleeding from esophageal varices and the use of reconstructive interventions.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):134-136
134-136
PREVENTION OF SYNDROME OF ACUTE LESION OF THE STOMACH IN PATIENTS OF PURULENT SURGICAL DEPARTMENT
Abstract
The article presents the analysis of published data on the risk factors for development of acute erosive-ulcerative lesions of the upper gastrointestinal tract in patients of purulent surgical department. The results of the own research of this problem are presented.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):137-139
137-139
A BRIEF HISTORY OF SAMARA HERNIOLOGICAL SCHOOL
Abstract
The article is devoted to the history of Samara herniological school from its foundation to the present time. The paper presents the most important research works of scientists of Samara devoted to the problems of treatment of patients with abdominal hernias of various localization.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):140-143
140-143
IN THE WAKE OF XXV RUSSIAN SYMPOSIUM«MODERN ASPECTS OF SURGICAL ENDOCRINOLOGY»
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):144-146
144-146
TECHNOLOGY AND SCOPE OF OPERATIONS IN PATIENTS WITH PRIMARY AND TERTIARY HYPERPARATHYROIDISM
Abstract
Purpose: improving outcomes in patients with primary and tertiary hyperparathyroidism by the study of techniques and the volume of intervention in the thyroid and parathyroid glands. Materials and methods. The analysis of treatment of 52 patients with hyperparathyroidism was carried out: 21 patients with primary and 31 patients with tertiary hyperparathyroidism. Among them there were 15 men (28.8%) and 37 women (71.2%). The age of patients ranged from 20 to 80 years. In 71.4% of patients with primary and 77.4% with tertiary hyperparathyroidism the parathyroid gland pathology was combined with pathology of the thyroid gland. In patients with primary hyperparathyroidism, the operation was aimed at the removal of adenomas with high activity and maintenance of unaltered parathyroid glands. In patients with tertiary hyperparathyroidism, it was aimed at total parathyroidectomy. In case of combined pathology in organs, subtotal resection of the thyroid or thyroidectomy was performed. The operation technique is described in detail. Results. In addition to the removal of adenomas in 21 patients with primary hyperparathyroidism, subtotal resection of the thyroid gland was performed in 3 patients, and 12 patients underwent thyroidectomy. Among 31 patients with tertiary hyperparathyroidism, 17 patients had a multi-colloid goiter, which required performing thyroidectomy. Also while searching for parathyroid adenomas, 7 patients required mobilization of the thyroid gland, which was completed by its resection. Conclusion. 55.7% of patients with hyperparathyroidism have a combination of parathyroid and thyroid diseases, which requires implementation of thyroidectomy and removal of adenomas of parathyroid glands. In 19.2% of patients with hyperparathyroidism, the peculiarities of parathyroid adenoma location requires mobilization of the thyroid gland, which causes resection of the thyroid gland and removal of parathyroid adenomas.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):147-150
147-150
THYROIDECTOMY TECHNIQUE AS THE BASIS FOR IMPROVING THE RESULTSOF TREATMENT OF PATIENTS WITH BENIGN THYROID DISEASE
Abstract
Objective: improving outcomes of treatment of patients with diffuse and mixed toxic nodular euthyroid goiters by justification of thyroidectomy and prevention of complications at its performance. Materials and methods. The analysis of the results of thyroidectomy was performed in 243 patients who had diffuse toxic (60/24.7%) and mixed-toxic (86/35.4%) goiter, and also nodular euthyroid goiter (97/39.9%). The patients were divided into two groups according to the method of thyroidectomy. The first group included patients who underwent thyroidectomy performed from the isthmus, the second group - from the side surfaces of the thyroid gland. Results. After thyroidectomy from the isthmus without visualization of recurrent laryngeal nerves in 57 patients, there was a violation of phonation in 8 (14%) patients, after thyroidectomy in a single block from the lateral surfaces of thyroid lobes with visualization of the location of recurrent laryngeal nerves - in 2 (1.07%) patients with substernal goiter. Conclusion. Thyroidectomy technique from the side surfaces of the thyroid gland with preservation of the inferior thyroid artery and ligation of branches reaching the thyroid gland under control of recurrent laryngeal nerves provides the minimal risk of development of phonation disorders.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):151-154
151-154
SURGICAL TREATMENT OF UREMIC TUMORAL CALCINOSIS IN PATIENTS WITH TERTIARY HYPERPARATHYROIDISM
Abstract
Objective - to work out tactics and techniques of operation in patients with tertiary hyperparathyroidism associated with uremic tumoral calcinosis. Materials. Tactics and methods of treatment of uremic tumoral calcinosis are not well-described because of the rarity of the pathology. The article presents clinical observation of the patient A. born in 1954. Diagnosis: chronic renal failure, tertiary hyperparathyroidism, parathyroid adenoma, osteo-articular form; uremic tumor calcification in the right shoulder and arm. Ca = 2,4-2,55 mmol / l, P = 1,7-1,8 mmol / l iPTH = 800 pg / ml. Result. Treatment of patient was carried out in two stages. The first step was removal of 6 parathyroid adenomas, the second - opening three calcification cysts in the right upper limb - 750 ml in total volume, containing white exudate resembling lime solution. The postoperative period was uneventful. IPTH = 60 pg / ml. Conclusion. 0.09% of patients with chronic renal failure on hemodialysis may develop uremic tumoral calcinosis, the treatment of which is aimed at excision of the parathyroid gland adenomas, opening and drainage of para-articular pathologic cysts.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):155-157
155-157
REPEATED SURGICAL INTERVENTIONS IN THE RECURRENCE AND REGIONAL METASTASES OF THYROID CANCER
Abstract
The article is devoted to repeated surgical interventions in patients with differentiated forms of thyroid cancer. The results of surgical treatment of patients with local recurrence and regional metastasis of thyroid cancer were analyzed. According to the results of own experiments, conclusions on the tactics of management of patients with this pathology were formulated.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):158-160
158-160
EMERGENCY OPERATIONS IN PARATHYROID SURGERY
Abstract
The article deals with analysis of urgent situations in parathyroid surgery. Six patients out of 214, who underwent surgery in 2000-2013, were operated urgently. Three patients out of five, who underwent surgery associated with hypercalcemic crisis, died in immediate postoperative period. Surgery was indicated to one patient with compression of organs located in the neck region.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):161-164
161-164
QUALITY OF LIFE OF PATIENTS WITH NODULAR EUTHYROIDGOITER IN THE LATE POSTOPERATIVE PERIOD
Abstract
This article is devoted to the quality of life of 70 patients, who were operated for nodular and multinodular euthyroid goiter in the surgical department of Clinical Road Hospital on station Samara in 2005-2012. The study was conducted using a specific questionnaire evaluating the severity of relevant symptoms of patients with benign thyroid disease and general SF-36 questionnaire. It is shown that severe symptoms in the late postoperative period are neurological (cognitive), cardiac and emotional. Quality of life of patients who have undergone organ operations is significantly higher than after total thyroidectomy.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):165-169
165-169
THE DISEASE VON HIPPEL-LINDAU TYPE 2C (VHL SYNDROME)IN TWO GENERATIONS OF ONE FAMILY
Abstract
The disease von Hippel-Lindau (VHL) is an autosomal dominant inherited disease characterized by predisposition to various cancers. It is caused by a mutation of the 3rd chromosome at the site 3p25/26, where suppression gene of tumor growth is localized. The clinical course of the disease is divided into two types: type 1 - without development of pheochromocytoma (an affection of the retina, tumors of the brain and spinal cord, pancreatic, renal, and splenic cysts, solid pancreatic tumors), type 2 - with the development of pheochromocytoma (subdivided into subtype 2A with a low risk of development of kidney cancer, 2B - high risk of developing kidney cancer, 2C - development of only pheochromocytomas). The paper presents authors’ own observation of the family in two generations with type 2C VHL syndrome.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):170-172
170-172
PRACTICE OF SURGICAL TREATMENTOF TERTIARY HYPERPARATHYROIDISM
Abstract
Tertiary hyperparathyroidism (THPT) is a disease often followed by adenomatous transformation and autonomation of parathyroid glands; it is more common in patients older than 50, who are on hemodialysis. Ultrasonic examination and scintigraphy with Tc99m of parathyroid glands reveals only 70-75% cases of parathyroid adenoma. That is why the examination must include MRT (magnetic resonance tomography) of parathyroid glands. After surgery, patients with THPT need constant follow-up because of possible relapse.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):173-175
173-175
CARNEY COMPLEX, ASSOCIATED WITH ENDOGENOUS HYPERCORTISOLISM
Abstract
We present a clinical case of endogenous hypercortisolism. After examination, 18-year-old patient was diagnosed with Cushing's syndrome, presumably caused by corticosteroma of left adrenal gland. Left laparoscopic adrenalectomy was performed. Pathologohystological conclusion was adrenal pigmented nodular dysplasia. In postoperative period hypercortisolism symptoms regressed. During the 2-year lasting observation of patient no relapse was found. In retrospect, the patient revealed symptoms of a rare hereditary disease - Carney complex. The interest of submitted observation lies in its exceptional rarity. Unilateral adrenalectomy was effective, but the probability of recurrence of Cushing’s syndrome and other manifestations of Carney complex still exists.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):176-179
176-179
CLINICAL FEATURES OF PRIMARY HYPERPARATHYROIDISM IN PATIENTS WITH UROLITHIASIS
Abstract
Patients with PHPT combined with urolithiasis are a special group of patients, which is characterized by some epidemiological, clinical and biochemical features. The most notable features were hypercalcemia and male to female ratio. Both parameters were higher in the group with urolithiasis. The incidence of urolithiasis in PHPT population was 28.1%. In patients with urolithiasis calcium levels were significantly higher (3.1 vs. 2.57 mmol / l). They were younger (49.5 vs. 55.4 years) and among them there were more men (male to female ratio - 1:5 to 1:10,5).
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):180-184
180-184
CAN WE CONSIDER THE VOLUME OF THYROID REMNANT THE ONLY RISK FACTOR FOR RECURRENCE OF HYPERTHYROIDISM?
Abstract
The article presents long-term results of treatment of 58 patients with diffuse toxic goiter after surgical subtotal resection of the thyroid gland. The analysis of risk factors for recurrence of hyperthyroidism was performed. It was concluded that the volume of thyroid remnant is not prognostically significant factor in the risk of recurrence of hyperthyroidism.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):185-188
185-188
DIAGNOSTIC TACTICS BASED ON THE SYSTEM TIRADS
Abstract
The study was performed on 13532 ultrasound protocols and results of 4415 biopsies of thyroid nodules. The research demonstrated high potential of TIRADS system. TIRADS system helps to define the indications for biopsy and to form the risk groups. It focuses attention of cytologists on the probability of detecting tumors of the thyroid gland.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):189-192
189-192
211-215
COMMUNITY-ACQUIRED PNEUMONIA IN THE PRACTICE OF A PHYSICIAN IN PULMONOLOGY CENTER
Abstract
The analysis of the data of patients hospitalized with the diagnosis of “community-acquired pneumonia” to the pulmonology center based in Samara City Hospital №4 over the period two years was carried out. Every year the highest number of hospital admissions is registered among young patients of working age, mainly men. One of the main causes of mortality in patients with community-acquired pneumonia remains HIV-infection, often at the stage of severe immunosuppression. Meanwhile, the commitment to highly active antiretroviral therapy (HAART) in patients with HIV-infection and community-acquired pneumonia is 5,14%. The number of newly diagnosed patients with tuberculosis (TB) also remains high (17%) and requires the active cooperation of pulmonology and TB-services.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):216-218
216-218
OPTIMIZATION OF PATIENTS’ SELECTION FOR INTERVENTIONAL TREATMENT OF ATRIAL FIBRILLATION AND PREDICTORS OF ITS RECURRENCE AFTER CATHETER ABLATION
Abstract
We analyzed possible predictors of recurrence of atrial fibrillation after catheter ablation with the subsequent formation of a mathematical model predicting the efficacy of interventional treatment. This approach makes it possible to optimize the selection of patients with atrial fibrillation for radiofrequency ablation and increase its effectiveness.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):219-222
219-222
MICROCIRCULATION DISTURBANCES IN PATIENTS WITH POLYCYTHEMIA VERA AND ARTERIAL HYPERTENSION
Abstract
This article presents the features of the processes of microcirculation in patients with polycythemia vera and hypertension. Microcirculation was assessed using laser Doppler flowmetry. It was found that the studied patients mainly showed spastic type of microcirculation, which is characterized by the decrease in the arithmetic mean value of perfusion and the increase in average flow reserve. The increase in the bypass rate was determined. The revealed features of microcirculation indicate the increased risk of cardiovascular complications in observed patients.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):223-226
223-226
PRIMARY IMMUNODEFICIENCY IN SAMARA REGION
Abstract
The article is devoted to the peculiarities of the disease in patients with primary immunodeficiency (PID) in the Samara region. We studied the anamnestic and clinical features of the PID according to the patients’ medical histories. It was revealed that infectious respiratory diseases prevail among manifestations of PID. In addition, we came to the conclusion that PID is underdiagnosed.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):227-229
227-229
ROLE OF ULTRASONIC SCREENING IN DETECTING PATHOLOGY IN THE ADULT POPULATION
Abstract
The article focuses on the role of the ultrasonic method in the early diagnosis of disease in the adult population. The results of authors’ studies have shown that systemic echographic examination in 33.64% of patients who considered themselves healthy revealed the disease before clinical manifestations.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):230-232
230-232
INFLUENCE OF INTRADERMAL AUTO-SERUM THERAPY ON THE LEVEL OF IGE-ANTIBODIES IN CHILDREN WITH ATOPIC BRONCHIAL ASTHMA
Abstract
Objective: study of the influence of intradermal auto-serum therapy on the level of IgE-antibodies in children with atopic BA (bronchial asthma). Methods. A course of intradermal auto-serum therapy was conducted in 44 children with atopic BA with sensitization to house dust mite allergens. The quantitative analysis of IgE-antibodies to the mixed of mites D. pteronyssinus and D. farinae in serum was performed before the course of auto-serum therapy and afterwards. Results. There was a statistically significant decrease of the levels of IgE-antibodies to the mixed of mites D. pteronyssinus and D. farinae (p=0,0000001) after the course of auto-serum therapy. Conclusion. Intradermal auto-serum therapy leads to the decrease of the level of IgE-antibodies in children with atopic BA.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):233-236
233-236
LONG-TERM PROGNOSIS PREDICTION IN MYOCARDIAL INFARCTION INPATIENT TREATMENT BASED ON MYOCARDIAL ELECTRICAL INSTABILITY
Abstract
Analysis of clinical complications finding and hi-res three-channel holter monitoring records in patients with myocardial infarction allowed to develop of a prediction model for follow-ups of acute cardiac events (sudden cardiac death, strokes, recurrent myocardial infarction) prior to hospital discharge and within the first year after disease onset using the parameters of myocardial electical instability, arrhythmias and their dynamics.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):237-241
237-241
OPTIMIZATION OF RESPIRATORY SUPPORT IN THE ICU FOR ACUTE RESPIRATORY FAILURE
Abstract
The article is devoted to optimization of the respiratory support of patients with acute respiratory distress in the first hours of hospitalization in the intensive care unit and intensive pulmonary therapy profile for gas composition of arterial blood. The study presents two groups of patients: in the first group the respiratory support was administered by standard pulseoximetry (SatO2), and in the second group it was administered only after the analysis of gas composition of arterial blood. The results of own study confirmed that pulseoximetry (SatO2) is not sufficiently informative when choosing a method of respiratory support, and analysis of gas composition of arterial blood will help to optimize the treatment of acute respiratory failure in conditions of resuscitation and intensive therapy.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):242-245
242-245
THE IMPORTANCE OF METABOLISM COMPONENTS IN OBESITY. LITERATURE REVIEW
Abstract
Obesity is one of the most studied and as well disputed diseases in medical science. By now there opened many pathogenic factors influencing its development, evolution and prognosis: energetic, hormonal, genetic. However, not all of them are univocal and have established order of the occurrence. The greatest attention is paid to those which have practical output concerning correction of excess weight and the ability to achieve a stable result. Nevertheless, researches are ongoing, requiring all new terms and definitions and giving rise to more questions than answers.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):246-251
246-251
CHARACTERISTICS OF PATIENTS WITH CHRONIC VIRAL HEPATITIS IN THE SAMARA REGION
Abstract
The purpose of the research is to give description of patients with CVH observed in the Samara regional hepatological centre of Samara State Medical University and to identify groups for antiviral therapy based on its potential effectiveness for known predictors: gender, age, presence of HBeAg, viral load, genotype of the virus. 336 of CVH patients aged 18 to 78 years with disease duration from 3 to 12 years were observed. Examination of patients by the standard criteria for patients with chronic viral hepatitis showed that among patients with chronic viral hepatitis В in Samara region the main group of patients is HBV DNA «+», HBeAg-negative, genotype D. Among 336 patients 65.5% of the observed patients are subject to antiviral therapy, 18.4% of which have high probability of achieving SVR. In the rest 47.1% of patients it is necessary to consider the ratio of cost of treatment, its effectiveness, motivation of the patient that requires an individual approach in each case.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):252-255
252-255
CLINICAL AND LABORATORY CHARACTERISTICS OF INFECTIOUS MONONUCLEOSIS ASSOCIATED WITH EPSTEIN-BARR VIRUS INFECTION IN ADULTS (LITERATURE REVIEW)
Abstract
This review presents modern data of different aspects of infectious mononucleosis among adults. On the basis of scientific literature, the main etiological factors that lead to the progress of this disease, pathogenesis, and the most typical clinical forms of the disease among adults were specified. The article reflects clinical and laboratory features of infectious mononucleosis among adults.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):256-260
256-260
TO THE QUESTION OF THE RIGID EXTENSION OF THE PUPIL DURING CATARACT EXTRACTION
Abstract
The article presents the results of phacoemulsification with the use of the proposed method of rigid extension of the pupil, which allows the surgeons to reduce the operating injury, to protect pupillary edge of the iris, to achieve mydriasis of predetermined value, to reduce the likelihood of intra- and postoperative complications in patients with pseudoexfoliation syndrome.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):261-263
261-263
THE INCIDENCE OF GLAUCOMA IN THE SAMARA REGION OVER THE LAST 5 YEARS: TRENDS AND PROSPECTS
Abstract
Statistical information on morbidity, disability and prevalence of glaucoma determines the needs of the population in eye care for glaucoma patients, which in turn is the basis of network of the antiglaucoma service. Clinical and epidemiological analysis will help to identify the measures for improving the organization and the quality of eye care for glaucoma patients in the Samara region.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):264-268
264-268
VARIATIONS OF CLINICAL COURSE OF ASYMPTOMATIC VITREOMACULAR ADHESION
Abstract
In the article, the peculiarities and options of the clinical course of asymptomatic vitreo-macular adhesion are studied; possible outcomes and complications of macular area are analyzed. Monitoring of patients allowed us to identify three options of the clinical course of asymptomatic vitreo-macular adhesion: stable, camaraderie with the formation of a complete posterior vitreous detachment, and transition of asymptomatic vitreo-macular adhesion into symptomatic one with severe macular complications.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):269-273
269-273
ANALYSIS OF REMOTE RESULTS OF USING OF VARIOUS ORBITAL IMPLANTS AFTER ENUCLEATION, EVISCERATION, AND DEFERRED GRAFTING OF THE STUMP
Abstract
After removal of the eyeball, patients have problems related to psychological and social adaptation in society, which in turn requires medical and cosmetic rehabilitation of these patients. One of the most frequent causes of enucleation are eye injuries and their consequences. Therefore, there are many young patients of working age among patients with this pathology, which makes this problem socially significant. The solution of psychological and cosmetic problems in these patients can be creation of the musculoskeletal stump with the use of the orbital implant, which provides high-quality ocular prosthetics in this group of patients.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):274-277
274-277
COMPARISON OF BIOMETRICS CORNEA IN PRIMARY OPEN-ANGLE AND PRIMARY ANGLE CLOSURE GLAUCOMA
Abstract
The article is devoted to assessing the state of the central corneal thickness in different forms of primary glaucoma. The results of the study of the central corneal thickness in patients with primary open-angel (POAG) and angel closure (PACG) glaucoma compared with the control group of healthy individuals. According to the study, in the POAG central corneal thickness was significantly smaller than in PACG and in the control group. In the PACG «thin» and «ultrathin» corneas occurred twice rarer and “thick” and “ultrathick” ones occurred almost twice more frequently in comparison with POAG. The research also revealed an inverse relationship of the central corneal thickness values depending on the stage of glaucomatous process.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):278-280
278-280
CONE-BEAM COMPUTED TOMOGRAPHY IN THE DIAGNOSIS AND TREATMENT OF CHRONIC MAXILLARY SINUSITIS
Abstract
CBCT was performed in the treatment of 505 patients with pain syndrome of the maxillofacial area and 906 patients in preparation for surgery. Chronic sinusitis was detected in 418 patients (29.6 %), among which 147 (35.2 %) were diagnosed rhinogenous cause of the pathological process, 218 (52.1 %) - odontogenic, in 53 (12.7 %) the cause could not be determined because of the presence of pathological processes in the nasal cavity and in the teeth area. Sanitation of the maxillary sinus was performed in collaboration with an otolaryngologist, which contributed to the elimination of the inflammatory process at the dental clinic.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):281-283
281-283
COMPUTED TOMOGRAPHY IN DIAGNOSTICS AND TREATMENT PLANNING OF NONCARIOUS LESIONS
Abstract
Cone-beam computed tomography (CBCT) was applied in diagnostics and planning of treatment in 73 patients with noncarious lesions. For the first time, the density of hard tissues was estimated by the Hounsfield scale, which allowed accurate identification of areas of hypermineralization and demineralization. Presented data were used for determination of invasion areas at preparation for the operation. 3-D model and estimate indicators of the lesion area size helped to specify the type, form and rate of the noncarious lesion.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):284-286
284-286
287-289
ANALYSIS OF STRESSES IN THE BONE TISSUE OF THE JAWS IN VARIOUS DESIGNS OF DENTAL IMPLANTS
Abstract
The article discusses the biomechanical aspects of the choice of dental implant at the bone deficit in the area of the proposed implant. The analysis of stresses in the bone tissue when using intraosseous and external-intraosseous implants is carried out.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):290-293
290-293
CORRECTION OF RHEOLOGICAL PROPERTIES OF SALIVA IN CHILDREN WITH PATHOLOGY OF THE GASTROINTESTINAL TRACT
Abstract
The paper studies the dental status in children with erosive gastritis and duodenitis, and provides the materials on the detection of changes in oral health in patients with somatic pathology compared to a group of healthy children. It was found that patients with inflammatory and destructive lesions of the stomach and small intestine showed significantly higher performance intensity of dental caries and periodontal tissue destruction. Changes were detected in the rheological characteristics of the saliva. The results of authors’ own studies have confirmed the effectiveness of the developed “Composition for the prevention of dental and periodontal diseases” in changing the surface tension of saliva, and as a consequence - decreasing the reduction of dental caries and the severity of inflammation in periodontal tissues.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):294-298
294-298
REGISTRATION OF VERTICAL MOVEMENTS OF THE MANDIBLE IN THE DIAGNOSIS OF TMJ DYSFUNCTION
Abstract
The study of vertical movements of the lower jaw with a random selection of research objects for the purpose of identifying the early signs of TMJ dysfunction showed the prevalence of the curvature of the vertical movements of the lower jaw up to 87.5%, among which bilateral S-shaped curvature occurs in 15.6% of cases.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):299-302
299-302
COMPLEX ETIOPATHOGENETIC TREATMENT OF STOMATALGIA
Abstract
The peculiarities of clinical course, psychoemotional state, pain level in stomalgia are considered, and also the algorithm of actions in case of this pathology is presented. In complex etiopathogenetic treatment of this pathology collaborative efforts of the dental therapist, dental orthopedist and neuropathologist are required.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):303-305
303-305
306-308
CLINICAL EVALUATION OF USE OF AUTOGENOUS BONE MODIFIED DENTAL IMPLANTS WITH CONTINUOUS POROSITY
Abstract
The aim of the study was to investigate the stability of the performance of dental implants based on titanium nonwoven material with continuous porosity, set by the traditional technology and the technology of autologous modification. To accomplish the objectives of the study, 19 patients with partial or complete lack of teeth in the lower jaw were operated and 55 implants were installed in the lower jaw. The findings suggest that autologous bone tissue included in the porous material optimizes dental implant osteointegration.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):309-312
309-312
COMPUTER STABILOMETRICS IN THE DIAGNOSIS AND TREATMENT MONITORING OF POSTURAL VIOLATIONS IN ELDERLY PATIENTS
Abstract
Postural violations (PV) is a topical issue for people of advanced age. Studying of features of postural control in elderly people by means of computer stabilometrics (CS) was the research objective. This technique also can serve as control of efficiency of performed therapy of PN. In literature, there are only single researches of change of the main rack in persons older than 60 years. Materials and methods. 138 patients, whose age fluctuated from 60 to 102 years (average 77.8+2.3 years) were examined and divided into three age groups with 46 people in each one: elderly, seniors and long-livers. Results of research testify to marked decrease in compensatory opportunities of maintenance of balance in people over 60; the growth in postural instability was also noted according to the increase in age. Prior to therapy, a significant increase in the area and length of statokineziograms, as well as in the speed of movement of the center of pressure was revealed; average value of the “average position of the center of pressure” parameter in the frontal and sagittal planes considerably differed from normal indicators. After carrying out a standard course of treatment, the average values of the Deviation, Way and Speed parameters decreased in comparison with similar values before treatment. The average value of the Area parameter proved to be the most sensitive to medical manipulations. Conclusion. The CS method allows specialists to carry out rather objective early diagnostics of PN in elderly patients and to evaluate their condition in dynamics.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):313-318
313-318
OPPORTUNITIES AND PROSPECTS OF APPLICATION OF INTRAVENOUS LASER THERAPY IN MILD AND MODERATE VASCULAR COGNITIVE DISORDERS
Abstract
Disorder of cognitive functions is one of the earliest manifestations of chronic cerebrovascular pathology in patients with various cardiovascular diseases. Mild and moderate cognitive disorders worsen quality of patients’ life, influencing their professional activity. However, early diagnostics of cognitive disorder allows its correction and also administration of adequate therapy of the basic disease. Results of research of efficiency and safety of application of intravenous laser therapy at mild and moderate vascular cognitive frustration are presented. The research included 120 patients with mild and moderate vascular cognitive disorders. Among them, 60 patients received standard treatment in combination with intravenous laser therapy, other patients made a group of comparison. It was established that affected by intravenous laser therapy, manifestations of cognitive disorders, first of all mnestic and visuospatial, decreased. Besides, the decrease in aggregation of erythrocytes was observed in the main group of patients.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):319-322
319-322
FOUNDATION FOR APPROACHES TO THE PHARMACEUTICAL ANALYSIS OF HERBAL MATERIALS AND PHYTOCHEMICALS OF CALENDULA OFFICINALIS
Abstract
The article described foundation for new approaches to the analysis of herbal materials and preparations of Calendula officinalis L. by use of complex methods such as the TLC analysis, spectrophotometric and high performance liquid chromatography (HPLC). Discovery of narcissin as a dominant and active flavonoid has diagnostic value that is beneficial for the purpose of standardization of herbal materials and phytopharmaceuticals of Calendula officinalis L. For the purpose of objective quality evaluation of herbal materials and phytochemicals new methods were developed that allow analysis of the main groups of biologically active substances - flavonoids.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):323-326
323-326
SOME “DANGEROUS” OCCURRENCES BY USING ABBREVIATIONS IN THE DRUG ADMINISTRATIONS TO THE PATIENTS (BASED ON DATES IN PROFESSIONAL LITERATURE)
Abstract
The world development of scientific research by using modern instrumental facilities results in the creation of new methods and approaches to patient’s treatment. The tendency to the efficiency of professional interaction leads to a large number of abbreviations which number is keeping steadily growing. However, their widespread using often can cause serious outcomes. This article is devoted to the problems of misunderstanding and misinterpretation of medical abbreviations used in the drug administrations which are described in English-language literature. The proposed classification of medical abbreviations interpretation will be useful for optimal communication between healthcare professionals.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):327-329
327-329
PHENOLIC COMPOUNDS AND OXIDOREDUCTASES ACTIVITY IN MEDICINAL PLANTS (REVIEW)
Abstract
The review contains data of the research of some oxidoreductases in medicinal plants according to vegetation stages, the relationship of their activity and isozyme spectrum with accumulation of phenolic biologically active compounds (flavonoids), the possibility of using the above mentioned oxidoreductase characteristics as markers of plant harvesting period.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):330-334
330-334
ANALYSIS RANGE OF PHARMACEUTICAL COMPANIES VOLGA FEDERAL DISTRICT
Abstract
The paper presents an analysis of the assortment policy of the enterprises operating in the sector of pharmaceutical production of the Volga Federal District. In particular, we analyzed the structure of the range, dosage forms and types of dosage forms. It was found that as of 01.01.2015 on the pharmaceutical market of the Volga Federal District (PFD) represented 26 pharmaceutical manufacturers, which produce 693 international nonproprietary names for drugs, which corresponds to the 3100 trade names. In the overall structure of assortment largest share of company-producers of Samara, Penza and Nizhny Novgorod regions. The results of this analysis will be used to develop computer programs and databases «The potential of the pharmaceutical industry PFD».
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):335-337
335-337
EVALUATION OF PERSONNEL POTENTIAL IN PHARMACEUTICAL MARKET OF THE VOLGA FEDERAL DISTRICT
Abstract
This paper presents an analysis of the human resource capacity of the pharmaceutical market of the Volga Federal District. It was found out that the problem of staff shortages is one of the urgent problems. The proportion of persons of retirement and pre-retirement age in the retail sector of the pharmaceutical market is about 30%. At the same time, the number of budget places in universities during the last five years has decreased by 37%. In five years about 10 500 pharmacy professionals will come to the pharmaceutical companies of the Volga region. Thus, the shortage of personnel will continue.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):338-341
338-341
PHARMACOGNOSTIC STUDY ON SUBSTANTIATION OF MULTIPLE USING OF SILYBUM MARIANUM (L.) GAERTN
Abstract
In the present paper the results of investigations on substantiation of multiple using of milk thistle [Silybum marianum (L.) Gaertn.] are discussed. As a result of the conducted research, the flagship approaches to produce soluble silymarin were studied. Perspective sorts of milk thistle [Silybum marianum (L.) Gaertn.] with the highest content of flavolignans were examined. The approaches to increase the bioavailability of silymar for inclusion in transdermal dosages forms were considered.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):342-346
342-346
347-349
THE STUDY OF PHENOLIC COMPOUNDS OF AERIAL AND UNDERGROUND ORGANS OF POTENTILLA RECTA L
Abstract
The qualitative and quantitative analyses of flavonoids and tannins contained in aerial and underground organs of Potentilla recta L. were done by using of thin layer chromatography and spectrophotometry. The quantitative content of the target biologically active compounds was determined.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):350-352
350-352
CLINICAL ASPECTS AND PECULIARITIES OF IMMUNE HOMEOSTASIS IN SKIN ALLERGIES
Abstract
The article presents the peculiarities of the clinical course of allergic skin diseases. The changes in humoral immunity and in the cytokines in the peripheral blood are revealed. Major changes in quality of life for allergic contact dermatitis, eczema and atopic dermatitis were identified.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):353-355
353-355
DIFFERENTATION OF CD34+ CELLS DERIVED FROM HUMAN CORD BLOOD TO MEGAKARYOCYTES AND PLATELETS EX VIVO
Abstract
Despite of the fact that the basic essentials of thrombocytopoesis are well known, there are still a lot of unanswered questions regarding to the mechanism of this process. And because of the very low frequency of megakaryocytes in bone marrow (<1%), they often need to be produced in cell culture in order to study the process. The development of the approaches for ex vivo production of megakaryocytic progenitors, megakaryocytes and platelets cuts a swath and opens a prospect for their use in clinical practice. This paper examines the protocol of using serum free medium with addition of thrombopoietin, stem cell factor, interleukin-6 and -9 for production of megakaryocytic progenitor and megakaryocytes from CD34+ cells derived from cord blood, which are capable to produce platelets.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):356-361
356-361
ANALYSIS OF COMPOSITION AND ANTIBIOTIC RESISTANCE OF MICROFLORA ISOLATED FROM PATIENTS IN INTENSIVE CARE UNIT
Abstract
This article is devoted to the analysis of the microflora spectrum that was isolated from patients of resuscitation and intensive care unit. The resistance of the main predominant microorganisms to the antimicrobial agents is described. The results of own studies have confirmed the need for the dynamic monitoring of the microbial scene in the hospital. The basic directions for prophylaxis and management of organizational work in the workplace in a laboratory are proposed.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):362-366
362-366
367-371
ANALYSIS OF WORKING TIME OF NURSES IN THE ONCOLOGICAL DEPARTMENT OF RESUSCITATION AND INTENSIVE THERAPY ACCORDING TO THE TIMING
Abstract
The article presents the analysis of working time of nursing staff on the example of ward nurses in the resuscitation and intensive care department for major and minor works by method of photochronometry of working day in the General hospital.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):372-375
372-375
APPROACHES TO IMPROVEMENT OF QUALITY OF MEDICAL REHABILITATION: EXPERIENCE OF THE CITY CENTER FOR MEDICAL REHABILITATION OF SAMARA CITY POLICLINIC №6
Abstract
The article describes the algorithm of rendering services in medical rehabilitation and experience of the city center for medical rehabilitation of Samara city policlinic №6. The analysis of patients’ satisfaction showed that all the patients were contented with quality of services in medical rehabilitation by the results of questioning of 100 patients treated in the Center for 6 months in 2015. Conclusion: presented approaches to improvement of quality management in the city center for medical rehabilitation increased the quality of medical rehabilitation, overall performance and satisfaction of consumers (the personnel and patients).
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):376-379
376-379
ANALYSIS OF INFORMATION NEEDS OF SENIOR NURSES
Abstract
The article is devoted to one of the current trends in the development of information technologies in medical practice of development and implementation of workstation. The introduction of a unified information system and the formation of information space will significantly reduce the time, increase productivity and the level of professional qualification of senior nurses.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):380-382
380-382
SOME ASPECTS OF HEALTH OF THE POPULATION
Abstract
The article presents the scientific assessment of the health of the population of Zhigulyovsk in Samara region with the medical and demographic aspects and morbidity statistics for the period of 2004-2013. The results of the study revealed population decline, largely due to the decreased inflow of migration; slowing down of the natural population decline in conditions of rising fertility and decreasing mortality; growth of the revealed pathology at high appealability of the population in health care organizations. The identified patterns allow using of the data as a basis for management decisions in the field of public health.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):383-386
383-386
MODERN ASPECTS OF MORTALITY AMONG RURAL POPULATION
Abstract
The paper presents the scientific assessment of mortality in the Volga rural district of Samara region for the period 2009-2013. There is a decrease in total mortality of the population against the background of stable fertility rates, resulting in a small natural population loss. The mortality rate from diseases of the circulatory system is decreasing, and mortality from neoplasms and injuries is increasing. For purpose of further mortality reduction, a set of measures, including preventive measures aimed at eliminating the risk of premature mortality, is required.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):387-390
387-390
THE EXPERIENCE OF BINARY LECTURES BY THE HEADS OF NURSING SERVICES IN HOSPITALS
Abstract
The article reviews the experience of the binary lectures by chief and senior nurses in hospitals. During a conversation, two lecturers demonstrate the interdisciplinary relationship between the problems of psychology and office management, transferring knowledge on the basis of integration; they show the development and improvement of intellectual, creative and communicative abilities of nursing managers. The study focuses on the principles of andragogy in the process of conducting lectures by two lecturers, including 3 simulated production situations from real practice of managers of nursing services.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):391-395
391-395
ORGANIZATION OF EXPERTISE OF TEMPORARY DISABILITY IN CITY HOSPITAL
Abstract
In order to improve the quality of medical care in a City Hospital, we studied the system of organization of expertise of temporary disability, which has a two-level structure that includes attending doctors and medical commission under the supervision of the heads of departments and deputy chief physician of the hospital. Despite the problems in health care system, the majority of patients and physicians are satisfied with the quality of care and solution of issues during the examination of temporary disability. Based on the survey and testing of physicians, organizational and management problems were identified, as well as difficulties in the organization of information support services during the examination of temporary disability.
Aspirantskiy Vestnik Povolzhiya. 2015;15(5-6):396-402
396-402