Vol 11, No 3 (2023)
- Year: 2023
- Published: 15.03.2023
- Articles: 10
- URL: https://ogarev-online.ru/2311-2468/issue/view/17250
Full Issue
Hygienic assessment of noise load on students of the faculty of foreign languages
Abstract
Noise pollution is a load that has a harmful and irritating effect on the human body, including full-time students. In this regard, it is necessary to control the level of noise pollution in higher education institutions, where they spend a large amount of time. The aim of the study is to determine the subjective indicators of noise pollution based on a survey of students. The survey involved 63 students of the Faculty of Foreign Languages of Ogarev Mordovia State University, who noted a decrease in attention and concentration, irritability, headaches, deterioration in the perception of written speech due to noise exposure.
Kidney damage in multiple myeloma. Analysis of a clinical case
Abstract
Multiple myeloma is a sluggish tumor disease of plasma cells. The etiological cause of myeloma, as well as many other blood diseases, is unclear. More often, men and women over 50 suffer from myeloma. The article considers a clinical case of a patient with multiple myeloma and kidney damage. The stages of the disease development, diagnostic search and modern methods of treatment are described.
Clinical case of hemorrhagic fever with renal syndrome in child
Abstract
Despite the fact that the proportion of the child population in the structure of the overall incidence of hemorrhagic fever with renal syndrome is small, the polymorphism of manifestations, the absence of specific methods of prevention indicate the importance of this problem in pediatrics. The article describes a clinical case of hemorrhagic fever with renal syndrome in a 15- year-old girl. The presented clinical observation indicates the difficulties in diagnosing the disease in children, making a differential diagnosis with diseases that occur with intoxication syndromes, fever, and kidney damage.
Analysis of obstetric and perinatal complications in patients with new coronavirus infection COVID-19
Abstract
A new coronavirus infection, which was given the status of a pandemic, opened up the problem of extragenital pathology of pregnancy in a new way. The physiological characteristics inherent in the gestation period make women a special risk group in the structure of the incidence of coronavirus infection. The risk of hospitalization in the intensive care unit in pregnant women with coronavirus infection is higher than in non-pregnant patients of childbearing age. Patients with coronavirus infection are more likely to experience complications of pregnancy and childbirth.
Nodal pathology of thyroid gland during gestation period: clinical picture and ultrasound characteristics
Abstract
The paper highlights the issues of the influence of pregnancy on the thyroid gland of a woman in conditions of iodine deficiency, and the influence of thyroid hormones on the course of pregnancy and fetal development. Nodular disease can manifest during the gestation period and require treatment. The study includes an analysis of the prevalence of thyroid nodules among patients in an obstetric hospital in the city of Tyumen.
Clinic, diagnosis and treatment of nonclostridial lung abscesses
Abstract
Nonclostridial lung abscesses have characteristic clinical features. This specificity makes it possible to establish a diagnosis in a timely manner and plan a complex of response therapeutic actions. We should use methods of local transthoracic sanitation more widely in the treatment of patients with peripheral localization of lung abscess if anaerobic nonclostridial infection is predominant.
In vitro study of the pharmacological efficiency of pyridinecarboxy acid derivatives
Abstract
Breast cancer is one of the most common types of malignant tumors in women, ranking second in the structure of mortality after lung cancer. To assess the role of reverse transport as a mechanism of primary resistance of tumor cells to new antitumor agents, two triple-negative human breast cancer cell lines were used, one of which expresses (cell culture MDA-MB-231 (HTB- 26), ATCC, USA) and the other does not express the breast cancer reverse transport protein BCRP (BT20, ATCC, USA). In this work, compounds of pyridinecarboxylic acids with laboratory codes LHT-13-19 and LHT-17-19 were studied. The presence of primary resistance to the LHT-13-17 compound and its absence to the LHT-17-19 substance, due to the reverse BCRP-mediated transport of the active substance molecules, was experimentally shown.
The effects of immune and microbiological factors on damage to central nervous system: an analysis of modern data
Abstract
Multiple sclerosis is a chronic disease of the central nervous system, which is accompanied by neurodegenerative processes and autoinflammatory reactions, leading to diffuse damage to the central and peripheral nervous system, the consequence of which is a decrease in the quality of life. One of the etiological factors in its development are c microorganisms, in particular human herpes virus type 4 and human herpes virus type 6.
Cytokine profile of the blood serum of women with recurrent miscarriage
Abstract
This literature review is devoted to the problem of recurrent miscarriage, in the pathogenesis of which an important role is played by the dysregulation of immune processes associated with an imbalance of pro- and anti-inflammatory cytokines. The prevalence of immunosuppressive mediators ensures the preservation and progression of pregnancy. In women with miscarriage, an increase in serum pro-inflammatory cytokines is determined, produced mainly by antigen-presenting cells and type 1 helper T-lymphocytes.
Nutritional status and health of schoolchildren in Mordovia
Abstract
To assess the impact of nutrition on the health of schoolchildren, including school meals, a cross-sectional epidemiological study of the health status of schoolchildren was conducted with elements of a retrospective analysis. A representative sample of students aged 7-17 was formed, in the amount of 286 people. It has been established that school-age children in the Republic of Mordovia have nutritional disorders (excess of salt, deficiency of polyunsaturated fatty acids and some vitamins), which in children of grades 1–4 was more optimal than in students of grades 5–11, possibly due to the provision of compulsory hot meals at school.