Vol 6, No 4 (2018)
- Year: 2018
- Published: 15.04.2018
- Articles: 10
- URL: https://ogarev-online.ru/2311-2468/issue/view/18511
Full Issue
The relationship of the level of secretory immunoglobulin A and Candida contamination of gastric mucosa
Abstract
The study shows the relationship of the level of secretory immunoglobulin A and of Candida contamination of the mucous membrane in chronic gastritis. 20 healthy volunteers and 60 patients with chronic gastritis of II-IV degrees were examined. In patients with chronic gastritis, when compared to healthy individuals, an increase in colonization of the mucosa of Candida species and the serum level of secretory immunoglobulin A, associated with the growth of the atrophy stage, was found. The positive correlation of the parameters in question is demonstrated.
Features of lesions of gastrointestinal tract in children with juvenile arthritis
Abstract
Currently, the problem of acquired lesions of the gastrointestinal tract in chronic inflammatory joint diseases in children is highly relevant. The results of the authors’ research and the analysis of scientific literature data shows a high representation of combined pathology of the digestive tract detected, as a rule, during instrumental examination and associated with Helicobacter (H.) pylori infection, high disease activity, regular intake of several anti-inflammatory drugs.
Rhythmic transcranial magnetic stimulation in rehabilitation of patients after stroke
Abstract
The article includes the research results of foreign and Russian scientists on the use of rhythmic transcranial magnetic stimulation (pTMS) for rehabilitation of more than 400 patients after stroke. The positive effect of this method on the coordination and strength of muscles with post-stroke violations of the motor functions of the upper and lower extremities is shown. The use of pTMS demonstrates a positive dynamics in restoring such complex skills as walking and speaking as well as increasing in overall activity and the effectiveness of household adaptation of post-stroke patients. The necessity of pTMS inclusion in the rehabilitation program of patients after stroke for the correction of motor and speech disorders is proved.
Selection of Staphylococcus species of nasal mucosa and studying antibiotic sensitivity of allocated strains
Abstract
Among the etiological factors in the development of nosocomial infections a special place is hold by the well-known and thoroughly studied gram-positive bacteria of the genus Staphylococcus. The nasal microbiota of 30 surgery interns aged 22-24 with no acute and chronic respiratory diseases was studied. The material sampling, the nasal microbiota studying and the detection of antibiotic sensitivity of staphylococci to traditional antibiotics was carried out in accordance with the standard procedures. The study results show that among apparently healthy interns 25 strains of bacteria of the genus Staphylococcus were allocated.
"Mysterious" lipoproteine (a) and atherogenesis: molecular-cell interactions
Abstract
The article includes a review of experimental and clinical studies on the role of lipoprotein (a) in the pathogenesis of cardiovascular pathology. The author analyzes its involvement in the expression of receptors on the cell surface, the activation of platelet aggregation, the migration of inflammatory cells and the induction of vascular remodeling.
A study of dimethyl sulfoxyde cytotoxicity by MTT-test on L929 cell culture
Abstract
The study objective was to investigate the cytotoxicity of dimethyl sulfoxide on the cell culture of the murine fibroblasts L929. The cytotoxicity was studied by the standard procedure of MTT-test. The сells were incubated during 24 hours. Then dimethyl sulfoxide in concentrations from 1 to 0,0625% (by titration 1 : 2) was added. The standard medium without dimethyl sulfoxide was added in equivalent amount as passive control. The exposition time of the studied substances was 48 hours. All experiments were repeated three times. It was found that dimethyl sulfoxide has cytotoxic activity on the cell culture of the murine fibroblasts L929 after 48 hours of incubation at 1 and 0,5% concentration. This fact should be taken into consideration if dimethyl sulfoxide is used as solvent for nonpolar lipophilic substances testing on the cell culture of the murine fibroblasts.
Population attitudes to health problems and level of awareness of risk factors of cardiovascular diseases
Abstract
The study includes an employee survey data obtained by means of anonymous questioning of the employees of the engineering department of Electrovypryamitel Ltd., Saransk city. 63 respondents aged 18 to 69 were interviewed. The survey participants were asked about their attitudes to health issues and awareness of the role of risk factors in cardiovascular diseases (CVD) development. The survey results show a high prevalence of CVD risk factors among the population and insufficient awareness of the respondents about them.
Gastrointestinal stromal tumors: definition, prevalence in the Russian Federation and the Republic of Mordovia
Abstract
The article deals with the issues of etiology and diagnosis of gastrointestinal stromal tumors (GISO). A detailed statistical report for the five-year period reflecting the features of GISO epidemiology in the Republic of Mordovia is provided. The figures obtained in the course of the study are presented in comparison with the total figures for the Russian Federation. The results can serve as a basis for further study of this pathology.
A study of some risk factors of lethal outcome of community-acquired pneumonia in in-patient city hospital
Abstract
The article presents a retrospective analysis of medical records of patients who died of pneumonia in the pulmonology department of a general hospital. The factors of lethal outcome of community-acquired pneumonia are defined: late hospitalization (5 days from the beginning of the disease); underestimation of seriousness of patient condition at primary examination; accompanying somatic pathology and bilateral pneumonia; mistakes of initial antibacterial therapy.
Assessment of awareness of viral hemorrhagic fevers and measures for their preventing among university students
Abstract
Тhe study objective was to examine the level of knowledge about the key measures for preventing viral hemorrhagic fevers and their application among the students of National Research Mordovia State University. The relations between the students' awareness and their age, specialty, frequency of visits to endemic countries, attitude towards annual medical examination, place of residence were identified.