Том 5, № 7 (2017)
- Жылы: 2017
- ##issue.datePublished##: 08.07.2017
- Мақалалар: 10
- URL: https://ogarev-online.ru/2311-2468/issue/view/18544
Бүкіл шығарылым
An assessment of high resolution ECG of patients with paroxysmal atrial fibrillation on prophylactic antiarrhythmic drugs
Аннотация
The study found that the prophylactic use of allapinin in patients with paroxysmal form of atrial fibrillation increases the electrical instability of the myocardium. The use of allapinin in combination with sotalol affected the indicators of late potentials of auricles, which exceeded the values of healthy individuals.


The influence of polymorphism of T-31C gene IL-1Β on the development of metabolic syndrome in patients with arterial hypertension
Аннотация
The aim of the research was to study the role of polymorphism of T-31C gene IL- 1β and its correlation with clinical and biochemical parameters in patients with arterial hypertension affected by metabolic syndrome and without it. The study found the close relationship of genotype С/С with increased body mass index and the heterozygous genotype C/T with high cholesterol.


3D modeling and 3D printing as a new stage in the development of vascular prosthetics
Аннотация
The article deals with the major problems of vascular prosthetics. The author the considers the potential and the necessity of 3D modeling, 3D printing, and new polymeric materials for the production of vascular prostheses. The requirements to these materials and the prosthesis are provided. A new model of the vascular prosthesis is presented.


The synthetic nature of medical knowledge and modern techno-science
Аннотация
The article presents a review of the modern techno-scientific stage of medicine development. Medicine is considered in the aspect of its structural and functional specifics and a special synthetic nature. In the e-health development the main role is given to the information and communication technologies, effectively interacting with medicine. The leading cognitive principles in synthetic medical knowledge are the clinical-anthropic principle and the principle of Good Clinical Practice.


The frequency of orbital complications of acute purulent sinusitis
Аннотация
The article presents a comparative analysis of orbital complications of purulent sinusitis in the Republic of Mordovia for different periods (the years of 2011–2017 compared to the years of 1974–1977). The research focuses on the fluctuations in the number of patients with purulent sinusitis during the study period as well as the clinic of orbital complications of sinusitis. An assessment of the quality of specialized medical care in the Republic of Mordovia is provided.


Doxorubicine and nanodoxorubicine impact on the life expectancy of rats in the presence of an experimental zajdel hepatoma
Аннотация
The aim of the research was to study the impact of doxorubicin and nanodoxorubicine on the life expectancy of rats in the presence of an experimental Zajdel hepatoma. A series of experiments was carried out on 120 rats weighing 170-200 g. The introduction of nanodoxorubicine in rats after the development of Zajdel ascitic hepatoma decreased the average level of ascites. The average life expectancy increased by 46%, which proves a positive oncostatic effect of the drug.




The effect of cardivascular development abnormalities on hemodynamic parameters
Аннотация
The study shows a high prevalence of cardiovascular development abnormalities in the population. The abnormalities structure is mainly presented by additional trabeculae and chords in the left ventricular cavity. The research demonstrates a significant change of hemodynamic parameters. The values, reciprocal to the indicators of stroke and minute volume of the heart, were reduced in individuals with cardiovascular development abnormalities. To obtain the correct values of hemodynamic parameters, it is recommended indexing them depending on the body surface of the subject, as this takes into account their individual characteristics – height and weight.


Pathogenesis of acute intestinal obstruction and its diagnostics and treatment alternatives
Аннотация
The article reviews the key etiological factors and mechanisms of the intestinal obstruction development. A detailed description of the acute intestinal obstruction pathogenesis is provided. The issues of modern diagnostics of the acute intestinal obstruction of various geneses, including the subclinical picture, are covered. The optimal diagnostic and treatment algorithms are presented.


Changes in mucosal microbiota of stomach and colon at gastric ulcer
Аннотация
The examination of patients with active gastric ulcer determined the isolation rate and number of microorganisms in the stomach and large intestine before and after treatment in comparison with similar indicators of healthy individuals. Signs of dysbiosis of the large intestine in patients during the treatment of acute exacerbations were identified 25% more often and required correction.

