99mTc-Oxiracetam as a Potential Agent for Diagnostic Imaging of Brain: Labeling, Characterization, and Biological Evaluation


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Oxiracetam was labeled with 99mTc using sodium dithionite (Na2S2O4) as a reducing agent. The influence exerted on the labeling yield by the amounts of the reducing agent and substrate, pH, temperature, and reaction time was studied to optimize the labeling process. Biodistribution studies show that the 99mTcoxiracetam complex is suitable as a highly selective tracer for brain imaging.

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M. Sanad

Labeled Compounds Department, Hot Laboratories Center

编辑信件的主要联系方式.
Email: drsanad74@gmail.com
埃及, Cairo

Kh. Sallam

Labeled Compounds Department, Hot Laboratories Center

Email: drsanad74@gmail.com
埃及, Cairo

D. Salama

Health Radiation Research Department (Radiodiagnosis Unit), National Center for Radiation Research and Technology

Email: drsanad74@gmail.com
埃及, Cairo

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