Comparison of Quantitative Analytical Techniques for Dabigatran in Blood Plasma of Humans with Knee Replacements

A. V. Kozlov; V. V. Smirnov; D. A. Sychev; P. O. Bochkov; V. V. Chistyakov; E. S. Stepanova; L. M. Makarenkova

doi:10.1007/s11094-019-02077-x

Comparison of Quantitative Analytical Techniques for Dabigatran in Blood Plasma of Humans with Knee Replacements

作者: Kozlov A.V.¹, Smirnov V.V.¹, Sychev D.A.², Bochkov P.O.³, Chistyakov V.V.⁴, Stepanova E.S.⁴, Makarenkova L.M.⁴
隶属关系:
1. I. M. Sechenov First Moscow State Medical University (Sechenov University)
2. Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
3. V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
4. Research and Education Center, Peoples’ Friendship University of Russia
期: 卷 53, 编号 8 (2019)
页面: 771-774
栏目: Article
URL: https://ogarev-online.ru/0091-150X/article/view/245993
DOI: https://doi.org/10.1007/s11094-019-02077-x
ID: 245993

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

Two different literature methods were used to compare the experimental efficacy and accuracy of dabigatran assays in blood of 30 patients with knee replacements. Blood plasma was collected from patients who underwent anticoagulant therapy and were administered the medicine at a dose of 220 mg. Residual and peak dabigatran concentrations were determined by HPLC-MS and HPLC-MS/MS.