Comparison of Quantitative Analytical Techniques for Dabigatran in Blood Plasma of Humans with Knee Replacements


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

Two different literature methods were used to compare the experimental efficacy and accuracy of dabigatran assays in blood of 30 patients with knee replacements. Blood plasma was collected from patients who underwent anticoagulant therapy and were administered the medicine at a dose of 220 mg. Residual and peak dabigatran concentrations were determined by HPLC-MS and HPLC-MS/MS.

Авторлар туралы

A. Kozlov

I. M. Sechenov First Moscow State Medical University (Sechenov University)

Хат алмасуға жауапты Автор.
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 119991

V. Smirnov

I. M. Sechenov First Moscow State Medical University (Sechenov University)

Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 119991

D. Sychev

Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF

Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 125993

P. Bochkov

V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences

Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 125315

V. Chistyakov

Research and Education Center, Peoples’ Friendship University of Russia

Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 117198

E. Stepanova

Research and Education Center, Peoples’ Friendship University of Russia

Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 117198

L. Makarenkova

Research and Education Center, Peoples’ Friendship University of Russia

Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 117198

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