Enviar artigo por via de e-mail Comparison of Quantitative Analytical Techniques for Dabigatran in Blood Plasma of Humans with Knee Replacements
- Autores: Kozlov A.V.1, Smirnov V.V.1, Sychev D.A.2, Bochkov P.O.3, Chistyakov V.V.4, Stepanova E.S.4, Makarenkova L.M.4
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Afiliações:
- I. M. Sechenov First Moscow State Medical University (Sechenov University)
- Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
- V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
- Research and Education Center, Peoples’ Friendship University of Russia
- Edição: Volume 53, Nº 8 (2019)
- Páginas: 771-774
- Seção: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/245993
- DOI: https://doi.org/10.1007/s11094-019-02077-x
- ID: 245993
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Resumo
Two different literature methods were used to compare the experimental efficacy and accuracy of dabigatran assays in blood of 30 patients with knee replacements. Blood plasma was collected from patients who underwent anticoagulant therapy and were administered the medicine at a dose of 220 mg. Residual and peak dabigatran concentrations were determined by HPLC-MS and HPLC-MS/MS.
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Sobre autores
A. Kozlov
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Autor responsável pela correspondência
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 119991
V. Smirnov
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 119991
D. Sychev
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 125993
P. Bochkov
V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 125315
V. Chistyakov
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 117198
E. Stepanova
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 117198
L. Makarenkova
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Rússia, Moscow, 117198
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