Отправить статью по E-mail Comparison of Quantitative Analytical Techniques for Dabigatran in Blood Plasma of Humans with Knee Replacements
- Авторы: Kozlov A.V.1, Smirnov V.V.1, Sychev D.A.2, Bochkov P.O.3, Chistyakov V.V.4, Stepanova E.S.4, Makarenkova L.M.4
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Учреждения:
- I. M. Sechenov First Moscow State Medical University (Sechenov University)
- Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
- V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
- Research and Education Center, Peoples’ Friendship University of Russia
- Выпуск: Том 53, № 8 (2019)
- Страницы: 771-774
- Раздел: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/245993
- DOI: https://doi.org/10.1007/s11094-019-02077-x
- ID: 245993
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Аннотация
Two different literature methods were used to compare the experimental efficacy and accuracy of dabigatran assays in blood of 30 patients with knee replacements. Blood plasma was collected from patients who underwent anticoagulant therapy and were administered the medicine at a dose of 220 mg. Residual and peak dabigatran concentrations were determined by HPLC-MS and HPLC-MS/MS.
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Об авторах
A. Kozlov
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Автор, ответственный за переписку.
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 119991
V. Smirnov
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 119991
D. Sychev
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 125993
P. Bochkov
V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 125315
V. Chistyakov
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 117198
E. Stepanova
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 117198
L. Makarenkova
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Россия, Moscow, 117198
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