电邮这篇文章 Antiarrhythmic Activity of the Flavonoid Fraction of Plantago Major L. Extract
- 作者: Khushmatov S.S.1, Makhmudov R.R.1
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隶属关系:
- A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
- 期: 卷 52, 编号 12 (2019)
- 页面: 992-995
- 栏目: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/245572
- DOI: https://doi.org/10.1007/s11094-019-01939-8
- ID: 245572
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详细
Antiarrhythmic activity of the flavonoid fraction of Plantago major L. extract (0.05 mg/mL) was studied. The studied fractions were found to lower the frequency of rat cardiac papillary muscle contractions with aconitine-induced (1 μM) arrythmia in vitro. An analysis of literature and experimental data suggested that the antiarrhythmic effects of the studied flavonoid fractions may have been related to functional modulation of Na+- and Ca2+-channels in cardiomyocytes.
作者简介
Sh. Khushmatov
A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
编辑信件的主要联系方式.
Email: Khushmatov_Sh.S@bk.ru
乌兹别克斯坦, 83 M. Ulugbek St., Tashkent, 100125
R. Makhmudov
A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan
Email: Khushmatov_Sh.S@bk.ru
乌兹别克斯坦, 83 M. Ulugbek St., Tashkent, 100125
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