Potentiometric Sensor for Benzylpenicillin Determination

Zh. A. Kormosh; N. A. Markovska; N. N. Kormosh

doi:10.1007/s11094-019-02040-w

Potentiometric Sensor for Benzylpenicillin Determination

Authors: Kormosh Z.A.¹, Markovska N.A.¹, Kormosh N.N.²
Affiliations:
1. Lesya Ukrainka Eastern European National University
2. Lutsk Basic Medical College
Issue: Vol 53, No 6 (2019)
Pages: 577-579
Section: Structure of Chemical Compounds, Methods of Analysis and Process Control
URL: https://ogarev-online.ru/0091-150X/article/view/245877
DOI: https://doi.org/10.1007/s11094-019-02040-w
ID: 245877

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Abstract

A potentiometric benzylpenicillin-sensitive sensor with a plasticized polyvinyl-chloride membrane was developed. The sensor contains a benzylpenicillin—rhodamine 6G ion pair. The response is linear for benzylpenicillin concentrations in the range 10^–3 – 10^–1M with an electrode-function slope characteristic of singly charged anions and a minimum detected concentration of (6.3 – 7.9) × 10^–4 M. This sensor could be used to detect and determine benzylpenicillin in pharmaceuticals.