Potentiometric Sensor for Benzylpenicillin Determination

Resumo

A potentiometric benzylpenicillin-sensitive sensor with a plasticized polyvinyl-chloride membrane was developed. The sensor contains a benzylpenicillin—rhodamine 6G ion pair. The response is linear for benzylpenicillin concentrations in the range 10^–3 – 10^–1M with an electrode-function slope characteristic of singly charged anions and a minimum detected concentration of (6.3 – 7.9) × 10^–4 M. This sensor could be used to detect and determine benzylpenicillin in pharmaceuticals.