Modulation of the Acetylcholine-Induced Input Current by Noopept in Helix Lucorum Neurons
- Авторлар: Murzina G.B.1, Pivovarov A.S.2
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Мекемелер:
- Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
- Department of Biology, Moscow State University
- Шығарылым: Том 64, № 3 (2019)
- Беттер: 393-399
- Бөлім: Cell Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/152952
- DOI: https://doi.org/10.1134/S0006350919030151
- ID: 152952
Дәйексөз келтіру
Аннотация
Abstract—Possible causes of the positive modulating effect of noopept (in a concentration range of 0.1 to 10 nM) on the amplitude of the acetylcholine-induced input current are analyzed using a developed mathematical model. The results revealed that the calculated and experimental current curves coincide when the number of nicotinic acetylcholine receptors on the neuron membrane is increased or the efficiency of muscarinic acetylcholine receptors is changed.
Негізгі сөздер
Авторлар туралы
G. Murzina
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: gbmurzina@mail.ru
Ресей, Moscow, 117485
A. Pivovarov
Department of Biology, Moscow State University
Email: gbmurzina@mail.ru
Ресей, Moscow, 119234
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