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发表评论 Correlation analysis of T2-weighted images and Medical Research Council scale in corticosteroid-naive patients with Duchenne muscular dystrophy
- 作者: Suslov V.M.1, Pozdnyakov A.V.1, Ivanov D.O.1, Rudenko D.I.1, Malekov D.A.1, Suslova A.D.1, Ulyanenko D.I.1
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隶属关系:
- St Petersburg State Pediatric Medical University
- 期: 卷 8, 编号 6 (2017)
- 页面: 72-79
- 栏目: Articles
- URL: https://ogarev-online.ru/pediatr/article/view/7879
- DOI: https://doi.org/10.17816/PED8672-79
- ID: 7879
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详细
Because of the necessity of objective instrumental methods for assessing the state of skeletal musculature in patients with Duchenne muscular dystrophy, the aim of our work was to evaluate the correlation between manual methods of assessment of the muscle strength and the results of magnetic resonance imaging (MRI) of the skeletal muscles of lower limbs. We have examined 15 corticosteroid-naive patients with Duchenne muscular dystrophy. Patients were divided into 2 groups: ambulant patients (average age 8.1 years) and non-ambulant patients (mean age 12.7 years). Muscle strength of lower extremities of all patients has been evaluated by Medical Research Council scale and MRI of skeletal muscles of the pelvic girdle, thighs and lower legs has been performed. The following results have been obtained: ambulant patients have been characterized by a high correlation of MRC scale and MRI of the lower extremities in the evaluation of the pelvic girdle and thighs muscles and the total score (pelvic girdle, thighs and lower legs) and salient correlation in the evaluation of the lower legs muscles. Non-ambulant patients have been characterized by moderate correlation in the evaluation of pelvic girdle and thighs muscles, as well as the total score of lower limbs. There was no correlation between MRC and MRI results in the muscles of the lower legs. Magnetic resonance tomography is able to reliably estimate the degree of fatty infiltration in Duchenne muscular dystrophy and is the method of choice in the diagnosis and evaluation of the severity of this disease.
作者简介
Vasiliy Suslov
St Petersburg State Pediatric Medical University
编辑信件的主要联系方式.
Email: vms.92@mail.ru
Assistant of the Department of Rehabilitation
俄罗斯联邦, Saint PetersburgAlexander Pozdnyakov
St Petersburg State Pediatric Medical University
Email: pozdnyakovalex@yandex.ru
PhD, Professor, Head of the Department of Radiology Diagnostic
俄罗斯联邦, Saint PetersburgDmitry Ivanov
St Petersburg State Pediatric Medical University
Email: doivanov@yandex.ru
MD, PhD, Dr Med Sci, Professor, Rector
俄罗斯联邦, Saint PetersburgDmitry Rudenko
St Petersburg State Pediatric Medical University
Email: dmrud_h2@mail.ru
PhD, Professor, Department of Rehabilitation
俄罗斯联邦, Saint PetersburgDamir Malekov
St Petersburg State Pediatric Medical University
Email: d.a.malekov@gmail.com
Radiologist, Department Of Radiology Diagnostic
俄罗斯联邦, Saint PetersburgAlexandra Suslova
St Petersburg State Pediatric Medical University
Email: fifa379@mail.ru
Student
俄罗斯联邦, Saint PetersburgDaria Ulyanenko
St Petersburg State Pediatric Medical University
Email: yaninul@yandex.ru
Student
俄罗斯联邦, Saint Petersburg参考
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