Email this article 
Post a Comment Autologous fat grafting in patients with volume restoration, soft tissues and skin defects correction
- Authors: Khramtsova N.I.1, Plaksin S.A.2, Sotskov A.Y.2, Ponomarev D.N.2
-
Affiliations:
- Ltd “Nalexya”
- E.A. Vagner Perm State Medical University
- Issue: Vol 39, No 4 (2022)
- Pages: 97-107
- Section: Methods of diagnosis and technologies
- URL: https://ogarev-online.ru/PMJ/article/view/110804
- DOI: https://doi.org/10.17816/pmj39497-107
- ID: 110804
Cite item
Full Text
Abstract
Objective. To analyze the results of fat grafting in volume restoration, soft tissues and skin defects correction.
Materials and methods. Autologous fat grafting was performed for aesthetic soft tissues correction in 30 women, as well as in 3 patients with long-term non-healing trophic ulcers to obtain a regenerative effect. Subcutaneous fat aspiration was implemented using standard liposuction techniques, water jet, mechanical and syringe.
Results. The volume of fat graft varied depending on the area requiring correction, and averaged 90 (33–195) ml. The areas, most often subjected to fat grafting, were the mammary glands – 10 (33 %), shins – 8 (27 %), buttocks – 5 (17 %), hands – 2 (7 %), lips and nasolabial region – 2 (7 %), the outer surface of the thigh – 1 (3 %). Despite partial decrease of fat graft volume in the postoperative period, all patients were satisfied with the results; no complications of the procedure were noted. The preparation of fat graft for the correction of trophic defects included its washing with saline and filtering with 1.4 and 1.2 mm anaerobic fat transfers; the fat was grafted through a 2 mm cannula into the subcutaneous tissue directly under and around the ulcerative defects. It improved the regeneration of the epithelium around the trophic ulcers and reduced their size.
Conclusions. Thus, the efficiency and safety of using the technique of autologous fat grafting for volumizing and regenerative purposes has been clinically confirmed.
Full Text
##article.viewOnOriginalSite##About the authors
N. I. Khramtsova
Ltd “Nalexya”
Email: danilpon07@gmail.com
Candidate of Medical Sciences, Chief Physician, surgeon, endoscopist
Russian Federation, PermS. A. Plaksin
E.A. Vagner Perm State Medical University
Email: danilpon07@gmail.com
Professor, Department of Surgery with Course of Cardiovascular Surgery and Invasive Cardiology
Russian Federation, PermA. Yu. Sotskov
E.A. Vagner Perm State Medical University
Email: danilpon07@gmail.com
sixth-year student
Russian Federation, PermD. N. Ponomarev
E.A. Vagner Perm State Medical University
Author for correspondence.
Email: danilpon07@gmail.com
sixth-year student
Russian Federation, PermReferences
- Simonacci F., Bertozzi N., Pio Grieco M., Grignaffini E., Raposio E. Procedure, applications, and outcomes of autologous fat grafting. Ann Med Surg (Lond). 2017; 20: 49–60.
- Billings E., Jr., May J.W., Jr. Historical review and present status of free fat graft auto transplantation in plastic and reconstructive surgery. Plast. Reconstr. Surg. 1989; 83: 368–381.
- Coleman S.R. Structural fat grafting. Aesthet. Surg. J. 1998; 18: 386–388.
- Coleman S.R. Long-term survival of fat transplants: controlled demonstrations. Aesthet. Plast. Surg. 1995; 19: 421–425.
- Piffer A., Aubry G., Cannistra C. et al. Breast Reconstruction by Exclusive Lipofilling after Total Mastectomy for Breast Cancer: Description of the Technique and Evaluation of Quality of Life. J. Pers. Med. 2022; 12 (2): 153.
- Rodby K.A., Kaptein Y.E., Roring J. et al. Evaluating Autologous Lipofilling for Parry-Romberg Syndrome-Associated Defects: A Systematic Literature Review and Case Report. Cleft. Palate. Craniofac. J. 2016; 53 (3): 339–350.
- Salibian A.A., Widgerow A.D., Abrouk M., Evans G.R. Stem cells in plastic surgery: a review of current clinical and translational applications. Arch. Plast. Surg. 2013; 40: 666–675.
- Gotland N., Rangatchew F., Khorasani H., Holmgaard R., Kølle S.F., Bonde C. Treating scars with lipofilling. Ugeskr Laeger 2018; 180 (26).
- Caruana G., Bertozzi N., Boschi E., Pio Grieco M., Grignaffini E., Raposio E. Role of adipose-derived stem cells in chronic cutaneous wound healing. Ann. Ital. Chir. 2015; 86: 1–4.
- Hammond S.E., Samuels S., Thaller S. Filling in the Details: A Review of Lipofilling of Radiated Tissues in the Head and Neck. J. Craniofac. Surg. 2019; 30 (3): 667–671.
- Tuganbekov T.U., Askarov M.B., Ashimov N.T., Saipieva D.T. Application of cellular technologies in the treatment of trophic ulcers. Klinicheskaya medicina Kazahstana 2013; 4 (30) (in Russian).
- Hovius S.E., Kan H.J., Verhoekx J.S., Khouri R.K. Percutaneous Aponeurotomy and Lipofilling (PALF): A Regenerative Approach to Dupuytren Contracture. Clin. Plast. Surg. 2015; 42 (3): 375-ix.
- Korableva N.P. Complications of liposuction and lipofilling: diagnosis, treatment and prevention: uchebnoe posobie. Saint Petersburg: SPbGPMU 2020 (in Russian).
- Shishmentsev N.B., Vasiliev V.S., Karpov I.A. Possibilities of regenerative surgery in the treatment of chronic venous and neuropathic ulcers of the lower extremities (literature review). Laser technologies in medicine. Lazernie tehnologii v medicine: sbornik nauchno prakticheskih rabot 2016; 160–166 (in Russian).
- Vasiliev V.S., Korchazhkina N.B., Mikhailova A.A., Nadelyaeva I.I., Vasiliev S.A., Vasiliev I.S., Vasiliev Yu.S., Teryushkova Zh.I., Kazantsev I.B., Vasilyeva E.S., Kotenko K.V. Modern technologies of regenerative recovery in patients with pathological cicatricial changes. Hirurgiya. Jurnal im. N.I. Pirogova 2021; 6 (2): 7–14 (in Russian).
- Kazantsev I.B., Tsukanov A.I., Vasiliev V.S. Free transplantation of adipose tissue as a method of reconstruction for lip deformities. Plasticheskaya hirurgiya i esteticheskaya medicina 2020; 3: 60–66 (in Russian).
- Advait V., Blake S. Autologous Fat Grafting For Facial Rejuvenation. Stat.Pearls. Publishing. 2022.
- Vasiliev V.S., Vasiliev S.A., Teryushkova Zh.I., Vasiliev Yu.S., Vasiliev I.S., Eremin I.I. Safety of clinical use of lipofilling and local injections of stromal vascular fraction of adipose tissue in cancer patients. Geni i kletki 2019; 14: 49 (in Russian).
- Cohen S., Sekigami Y., Schwartz T., Losken A., Margenthaler J., Chatterjee A. Lipofilling after breast conserving surgery: a comprehensive literature review investigating its oncologic safety. Gland Surg. 2019; 8 (5): 569–580.
- Piccotti F., Rybinska I., Scoccia E. et al. Lipofilling in Breast Oncological Surgery: A Safe Opportunity or Risk for Cancer Recurrence? Int. J. Mol. Sci. 2021; 22 (7): 3737.
- Bi H.S., Zhang C., Nie F.F., Pan B.L., Xiao E. Basic and Clinical Evidence of an Alternative Method to Produce Vivo Nanofat. Chin. Med. J. 2018; 131 (5): 588–593.
- Gause T.M., Kling R.E., Sivak W.N., Marra K.G., Rubin J.P., Kokai L.E. Particle size in fat graft retention: A review on the impact of harvesting technique in lipofilling surgical outcomes. Adipocyte. 2014; 3 (4): 273–279.
- Grabin S., Antes G., Stark G.B., Motschall E., Buroh S., Lampert F.M. Cell-assisted lipotransfer. Dtsch. Arztebl. Int. 2015; 112: 255–261.
- Teryushkova Zh.I. Vasiliev V.S., Vazhenin A.V., Vasiliev S.A. Treatment of radiation recotovaginal fistulas. Moskovskii hirurgicheskii jurnal 2019; 2 (66): 53–56 (in Russian).
Supplementary files
