To the issue of vagosympathetic balance assessment in patients with facial phlegmon
- Authors: Boev I.A.1, Yakovlev M.V.1
-
Affiliations:
- E.A. Vagner Perm State Medical University
- Issue: Vol 41, No 4 (2024)
- Pages: 64-69
- Section: Original studies
- URL: https://ogarev-online.ru/PMJ/article/view/267873
- DOI: https://doi.org/10.17816/pmj41464-69
- ID: 267873
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Abstract
Objective. To assess the influence of the autonomic nervous system tone on the activity of the inflammatory process in facial phlegmon.
Materials and methods. A group of patients with facial phlegmon (n = 74) was divided into two parts according to the predominant type of ANS. To identify the dominant type of ANS the method of A.M. Vayne was used. The content of leukocytes and their types was assessed in peripheral blood samples. The concentration of glucose, total protein, C-reactive protein was determined in the patients` blood serum. Statistical data processing was carried out using Student's t-test.
Results. Significant differences in laboratory parameters of patients with facial phlegmons with different types of the autonomic nervous system are demonstrated. In patients with prevailing sympathetic division, leukocytosis with a shift of the formula to the left was more pronounced. When the parasympathetic division dominated, a higher concentration of C-reactive protein was observed.
Conclusion. Assessment of the autonomic nervous system tone in case of facial phlegmons indicates its significant impact on the activity of the inflammatory process, which affects the duration of inpatient treatment.
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##article.viewOnOriginalSite##About the authors
I. A. Boev
E.A. Vagner Perm State Medical University
Author for correspondence.
Email: iosifboev@gmail.com
ORCID iD: 0000-0002-9682-7680
Degree Candidate of the Department of Dental Surgery and Maxillofacial Surgery, Dental Surgeon
Russian Federation, PermM. V. Yakovlev
E.A. Vagner Perm State Medical University
Email: iosifboev@gmail.com
ORCID iD: 0000-0002-2895-387X
Degree Candidate of the Department of Orthopedic Dentistry, Orthopedic Dentist
PermReferences
- Магаева С.В., Морозов С.Г. Нейроиммунофизиология. М.: ГУ НИИ биомедицинской химии им. В.Н. Ореховича РАМН 2005; 160 / Magaeva S.V., Morozov S.G. Nejroimmunofiziologija. Moscow: GU NII biomedicinskoj himii im. V.N. Orehovicha RAMN 2005; 160 (in Russian).
- Benarroch E.E. Autonomic-mediated immunomodulation and potential clinical relevance. Neurology 2009; 73 (3): 236–242. doi: 10.1212/WNL.0b013e3181aebd43
- Осипович О.А., Годовалов А.П. К вопросу о роли воспалительных заболеваний в развитии бесплодия у женщин. Медицинский альманах 2016; 45 (5): 85–87 / Osipovich O.A., Godovalov A.P. K voprosu o roli vospalitel'nyh zabolevanij v razvitii besplodija u zhenshhin. Medicinskij al'manah 2016; 45 (5): 85–87 (in Russian).
- Pongratz G., Straub R.H. Role of peripheral nerve fibres in acute and chronic inflammation in arthritis. Nat. Rev. Rheumatol. 2013; 9 (2): 117–126. doi: 10.1038/nrrheum.2012.181
- Machado M.P.R., Rocha A.M., de Oliveira L.F., de Cuba M.B., de Oliveira I.L., Castellano L.R., Silva M.V., Machado J.R., Nascentes G.A. N., Paiva L.H., Svin W. О, Junior V.R., Brum P.C., Prado V.F., Prado M.A. M., Silva E.L., Montano N., Ramirez L.E., da Silva V.J. D. Autonomic nervous system modulation affects the inflammatory immune response in mice with acute Chagas disease. Exp. Physiol. 2012; 97 (11): 1186–1202. doi: 10.1113/expphysiol.2012.066431
- Сергеенко Н.И., Юрченко С.А. Функциональная активность вегетативной нервной системы и уровень гормонов гипофиза у пациентов в предоперационном периоде. Новости хирургии 2011; 19 (1): 82–87 / Sergeenko N.I., Jurchenko S.A. Funkcional'naja aktivnost' vegetativnoj nervnoj sistemy i uroven' gormonov gipofiza u pacientov v predoperacionnom periode. Novosti hirurgii 2011; 19 (1): 82–87 (in Russian).
- Исмагилов М.Ф. Синдром вегетативной дисфункции: его издержки и актуальные проблемы. Неврологический вестник 2017; 49 (4): 62–68 / Ismagilov M.F. Sindrom vegetativnoj disfunkcii: ego izderzhki i aktual'nye problem. Nevrologicheskij vestnik 2017; 49 (4): 62–68 (in Russian).
- Боев И.А., Годовалов А.П., Штраубе Г.И., Антаков Г.И. Выраженность эндогенной интоксикации у пациентов с флегмоной лица и коморбидной патологией. Проблемы стоматологии 2018; 14 (1): 24–25 / Boev I.A., Godovalov A.P., Shtraube G.I., Antakov G.I. Vyrazhennost' jendogennoj intoksikacii u pacientov s flegmonoj lica i komorbidnoj patologiej. Problemy stomatologii 2018; 14 (1): 24–25. doi: 10.24411/2077-7566-2018-000014 (in Russian).
- Вагин Ю.Е., Деунежева С.М., Хлытина А.А. Вегетативный индекс кердо: роль исходных параметров, области и ограничения применения. Физиология человека 2021; 47 (1): 31–42. doi: 10.31857/S0131164622010155 / Vagin Ju.E., Deunezheva S.M., Hlytina A.A. Vegetativnyj indeks kerdo: rol' ishodnyh parametrov, oblasti i ogranichenija primenenija. Fiziologija cheloveka 2021; 47 (1): 31–42. doi: 10.31857/S0131164622010155 (in Russian).
- Kérdö I. Ein aus Daten der Blutzirkulation kalkulierter Index zur Beurteilung der vegetativen Tonuslage. Acta neurovegetativa. 1966; 29 (2): 250–268. doi: 10.1007/BF01269900
- Вейн А.М., Вознесенская Т.Г., Голубев В.Л. Заболевания вегетативной нервной системы. Под ред. А.М. Вейн. М.: Медицина 1991; 624 / Vejn A.M., Voznesenskaja T.G., Golubev V.L. Zabolevanija vegetativnoj nervnoj sistemy. Pod red. A.M. Vejn. Moscow: Medicina 1991; 624 (in Russian).
- Камышников В.С., Волотовская О.А., Ходюкова А.Б., Дальнова Т.С., Василиу-Светлицкая С.Г., Зубовская Е.Т., Алехнович Л.И. Методы клинических лабораторных исследований. Под ред. В.С. Камышникова. М.: МЕД пресс-информ, 2011; 751 / Kamyshnikov V.S., Volotovskaja O.A., Hodjukova A.B., Dal'nova T.S., Vasiliu-Svetlickaja S.G., Zubovskaja E.T., Alehnovich L.I. Metody klinicheskih laboratornyh issledovanij. Pod red. V.S. Kamyshnikova. Moscow: MEDpress-inform, 2011; 751 (in Russian).
- Sloan R.P., Cole S.W. Parasympathetic neural activity and the reciprocal regulation of innate antiviral and inflammatory genes in the human immune system. Brain Behav Immun. 2021; 98: 251–256. doi: 10.1016/j.bbi.2021.08.217.
- Undem B.J., Taylor-clark T. Mechanisms underlying the neuronal-based symptoms of allergy. j. Allergy. Clin. Immunol. 2014; 133 (6): 1521–1534. doi: 10.1016/j.jaci.2013.11.027
- Горшкова А.В., Русак Ю.Э., Русак С.Н., Ефанова Е.Н. Состояние вегетативной нервной системы у пациентов с хроническими дерматозами. РМЖ 2019; 27 (4): 59–61 / Gorshkova A.V., Rusak Ju.Je., Rusak S.N., Efanova E.N. Sostojanie vegetativnoj nervnoj sistemy u pacientov s hronicheskimi dermatozami. RMZh 2019; 27 (4): 59–61 (in Russian).
- Боев И.А., Штраубе Г.И., Антаков Г.И., Годовалов А.П. Эндогенная интоксикация у пациентов с флегмонами лица. Клиническая стоматология 2018; 85 (1): 54–57. doi: 10.37988/1811-153X_2018_1_54 / Boev I.A., Shtraube G.I., Antakov G.I., Godovalov A.P. Jendogennaja intoksikacija u pacientov s flegmonami lica. Klinicheskaja stomatologija 2018; 85 (1): 54–57. doi: 10.37988/1811-153X_2018_1_54 (in Russian).
- Okamoto L.E., Raj S.R., Gamboa A., Shibao C.A., Arnold A.C., Garland E.M., Black B.K., Farley G., Diedrich A., Biaggioni I. Sympathetic activation is associated with increased IL-6, but not CRP in the absence of obesity: lessons from postural tachycardia syndrome and obesity. Am J Physiol Heart Circ Physiol. 2015; 309 (12): H2098–107. doi: 10.1152/ajpheart.00409.2015.
- Lujan H.L., Di Carlo S.E. Physical activity, by enhancing parasympathetic tone and activating the cholinergic anti-inflammatory pathway, is a therapeutic strategy to restrain chronic inflammation and prevent many chronic diseases. Med. Hypotheses. 2013; 80 (5): 548–552. doi: 10.1016/j.mehy.2013.01.014
- Rosas-Ballina M., Ochani M., Parrish W.R., Ochani K., Harris Y.T., Huston J.M., Chavan S., Tracey K.J. Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia. PNAS. 2008; 105 (31): 11008–11013. doi: 10.1073/pnas.0803237105
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