Email this article MORPHOMETRIC DIFFERENTIAL DIAGNOSIS OF INTESTINAL TUBERCULOSIS AND CROHN’S DISEASE
- Authors: Fedorina T.A1, Nedugov G.V2
-
Affiliations:
- Samara State Medical University
- Samara Regional Bureau of Forensic Medical Expertise
- Issue: Vol 3, No 3 (2018)
- Pages: 57-60
- Section: Articles
- URL: https://ogarev-online.ru/2500-1388/article/view/21429
- DOI: https://doi.org/10.35693/2500-1388-2018-0-3-57-60
- ID: 21429
Cite item
Full Text
Abstract
Intestinal tuberculosis and Crohn’s disease are chronic granulomatous disorders that are difficult to differentiate histologically. Aim - to describe the case of erroneous establishment of Crohn's disease in a patient with intestinal tuberculosis by the results of pathomorphological examination of biopsy specimens of the colon. The absence of anti-tuberculosis therapy led to the progression of the tuberculosis process with the development of tuberculosis of the larynx, lungs and ileum, followed by disability of the patient. Conclusions. The given observation shows the necessity of introduction in the practice of clinical morphologist the morphometric methods of study of endoscopic biopsy specimens, allowing to differentiate between intestinal tuberculosis and Crohn's disease.
Full Text
##article.viewOnOriginalSite##About the authors
TA A Fedorina
Samara State Medical University
Email: fedorina_ta@list.ru
PhD, Professor, head of the Department of general and clinical pathology: pathological anatomy and pathological physiology of Samara State Medical University.
GV V Nedugov
Samara Regional Bureau of Forensic Medical Expertise
Email: nedugovh@mail.ru
PhD, head of the forensic-histological Department, the forensic examiner of Samara regional bureau of forensic analysis. ORCID iD 0000-0002-7380-3766
References
- Du J, Ma Y-Y, Xiang H, Li Y-M. Confluent Granulomas and Ulcers Lined by Epithelioid Histiocytes: New Ideal Method for Differentiation of ITB and CD? A Meta Analysis. Green J, ed. PLoSONE. 2014;9(10):e103303. I I doi: 10.1371/journal.pone.0103303 I PMID: I
- Pulimood A, Ramakrishna B, Kurian G et al. Endoscopic mucosal biopsies are useful in distinguishing granulomatous colitis due to Crohn’s disease from tuberculosis. Gut. 1999;45(4):537-541. PMID: 10486361^^^^^^^^^HII|HI^^^^^II
- Niriella MA, Kodisinghe SK, De Silva AP et al. Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a 7 case report. BMC Research Notes. 2016;9(1):417. I doi: 10.1186/s13104-016-2222-0 PMID: I
- Limsrivilai J, Shreiner AB, Pongpaibul A et al. Meta-Analytic Bayesian Model For Differentiating Intestinal Tuberculosis from Crohn’s Disease. American journal of gastroenterology. 8 2017;112(3):415-427. I doi: 10.1038/ajg.2016.529. PMID: I
- Ye Z, Lin Y, Cao Q, He Y, Xue L. Granulomas as the Most Useful Histopathological Feature in Distinguishing between Crohn’s Disease and Intestinal Tuberculosis in Endoscopic Biopsy Specimens. Wall. P, ed. Medicine. 2015;94(49):e2157. doi: 10.1097/MD.0000000000002157 PMID: 26656343
- Almadi MA, Ghosh S, Aljebreen AM. Differentiating intestinal tuberculosis from Crohn's disease: a diagnostic challenge. American journal of gastroenterology. 2009;104(4):1003-12. doi: 10.1038/ajg.2008.162 PMID: 19240705
- Kelly JH, Montgomery WW, Goodman ML, Mulvaney TJ. Upper airway obstruction associated with regional enteritis. Annals of otology, rhinology and laryngology. 1979;88(1Pt 1):95-99/ doi: 10.1177/000348947908800116 PMID: 426451
- Park S, Park J, Kim HK, Kim JY, Hur SC, Lee JH, Jung JW, Lee J. Tracheal Involvement in Crohn Disease: the First Case in Korea. Clinical Endoscopy. 2016;49(2):202-206. doi: 10.5946/ce.2015.059
Supplementary files
