Volume 11, Nº 13 (2023)
- Ano: 2023
- ##issue.datePublished##: 20.10.2023
- Artigos: 10
- URL: https://ogarev-online.ru/2311-2468/issue/view/17551
Edição completa
A clinical case of infectious mononucleosis
Resumo
Infectious mononucleosis is registered everywhere. The polymorphism of the symptoms of the disease causes difficulties in its clinical diagnosis. The purpose of the study is to present the main clinical manifestations and a case of infectious mononucleosis of own observation in a teenager. The onset of the disease proceeded under the guise of acute bronchitis followed by the development of highly active reactive hepatitis.
Disregulatory changes in surfactant and lung water balance in experimental brain ischemia and hypoxic preconditioning
Resumo
The results of the study of the surfactant system, water balance of the lungs, pro- and antioxidant activity of the lung tissue in experimental one-day incomplete global cerebral ischemia caused by bilateral occlusion of the common carotid arteries are presented. The effectiveness of early and late hypoxic preconditioning performed by means of cyclic hypoxic training prior to an ischemic episode was evaluated. The experiments were performed on male rats, including sham- operated and control ones. It has been established that under conditions of ischemia, the surface activity of the surfactant decreases, which is associated with the activation of lipid peroxidation and high activity of phospholipase hydrolysis, and the blood filling of the lungs increases. The use of early and late preconditioning does not eliminate dysregulatory disorders of surfactant and lung water balance.
Clinical and endoscopic characteristics of inflammatory diseases of the intestine in outpatient practice
Resumo
Inflammatory bowel disease occupies one of the leading positions in the structure of diseases of the gastrointestinal tract in terms of the severity of the course, the frequency of complications and mortality throughout the world. Late untimely diagnosis leads to an increase in the number of relapses, severe and complicated forms of the disease, which increases the frequency of major surgical interventions and disability in young patients of working age. The results of epidemiological studies indicate a constant increase in the incidence of this pathology in the world, including Russia.
Biological properties of the pathogens, diagnosis and treatment of gonococca infections at the present stage
Resumo
The article provides an analysis of data on the biological properties of Neisseria gonorrhoeae as the causative agent of gonorrhea and blennorrhea. Statistical data on morbidity, epidemiological features, and clinical manifestations of gonococcal infections are given. Methods of diagnostics and directions of treatment of gonorrhea are described.
Evaluation of changes in rats spermogram indicators with the combined use of liposomal cytostats and xymedon in the experiment
Resumo
Using of antioxidants is one of the main pathogenetically substantiated ways to reduce gonadotoxicity during chemotherapy with cytostatics. This article presents dynamic changes in the parameters of motility and viability of spermatozoa of rats with Walker-256 carcinoma with using a liposomal combination of doxorubicin and cyclophosphamide in combination with xymedon in free and liposomal forms.
Bacteriophage: characteristics and application features
Resumo
Resistance of common bacteria to antibiotics is reaching high levels in many countries. The list of effective antibacterial medicine is narrowing. Therefore, there is an increasing interest in phage therapy as an alternative or addition to antibiotic therapy. In this connection a survey was conducted among medical students aimed to find out their awareness of the issue.
Current approaches to the treatment of chronic rhinitis: a critical analysis
Resumo
The paper presents a critical analysis of the effectiveness of conservative treatment and surgery for chronic rhinitis. A conclusion is made that the effectiveness rates for chronic rhinitis treatment are increased with the combination of conservative treatment and surgery. As a result, the patient's quality of life is improved considerably.
Current issues of urogenital chlamydia
Resumo
The article presents the results of a survey carried out among the students of the 2nd and 6th years of the Medical Institute of the Ogarev Mordovia State University. The survey was aimed to study their level of knowledge about the methods of prevention and treatment of urogenital chlamydia. The survey results show a greater awareness of 6th year students in comparison with 2nd year students.
Noninvasive methods of diagnosis of electrical instability of the myocardium in children
Resumo
One of the urgent problems of modern pediatrics is the prediction of the development of electrical instability of the myocardium. The article reflects the risk factors, the pathogenetic mechanism of arrhythmias. The use of available non-invasive methods allows timely diagnosis of electrical heart instability in children. The parameters of the electrocardiogram are described, which reflect the processes of depolarization and repolarization of the ventricular myocardium, which make it possible to identify patients at risk for the development of life-threatening cardiac arrhythmias.
The effect of anaprilin and cardioxypine on the behavior of rats with drug-induced hyperthyroidism and anemia in the "open field" test
Resumo
The effect of anaprilin and its combination with cardioxypine (3-oxypyridine chloride) on the motor-behavioral reactions of white rats was studied using the model of combination of iron deficiency anemia and hyperthyroidism. It has been shown that the administration of anaprilin reduces horizontal and vertical motor activity and research activity. The additional use of cardioxypine prevents this decrease.