电邮这篇文章 Analysis of NAD and NAD-Dependent Protein Deacetylation in Mouse Tissues
- 作者: Solovjeva L.V.1, Panchenko A.V.2, Shabalin K.A.3, Nerinovski K.B.4, Yakimov A.P.3, Gubareva E.A.2, Svetlova M.P.1, Mudrak O.S.1, Khodorkovskiy M.A.5, Nikiforov A.A.1,5, Kulikova V.A.1,5
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隶属关系:
- Institute of Cytology, Russian Academy of Sciences
- Petrov National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
- Konstantinov Petersburg Nuclear Physics Institute of the National Research Center Kurchatov Institute
- St. Petersburg State University
- Peter the Great St. Petersburg Polytechnic University
- 期: 卷 12, 编号 6 (2018)
- 页面: 491-495
- 栏目: Article
- URL: https://ogarev-online.ru/1990-519X/article/view/212808
- DOI: https://doi.org/10.1134/S1990519X18060123
- ID: 212808
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详细
Nicotinamide adenine dinucleotide (NAD) plays a key role in the vital metabolic and regulatory processes in mammals. Disturbance of the NAD level regulation is associated with the development of such serious diseases as pellagra, neurodegenerative and cardiovascular disorders, diabetes, cancer and others. This paper presents an experimental approach that allows to determine the amount of NAD+ in mouse tissues using NMR spectroscopy, as well as the level of NAD+-dependent deacetylation of proteins in the cytosol and mitochondria.
作者简介
L. Solovjeva
Institute of Cytology, Russian Academy of Sciences
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 194064
A. Panchenko
Petrov National Medical Research Center of Oncology, Ministry of Healthof the Russian Federation
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 197758
K. Shabalin
Konstantinov Petersburg Nuclear Physics Institute of the National Research CenterKurchatov Institute
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, Gatchina, 188300
K. Nerinovski
St. Petersburg State University
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 199034
A. Yakimov
Konstantinov Petersburg Nuclear Physics Institute of the National Research CenterKurchatov Institute
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, Gatchina, 188300
E. Gubareva
Petrov National Medical Research Center of Oncology, Ministry of Healthof the Russian Federation
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 197758
M. Svetlova
Institute of Cytology, Russian Academy of Sciences
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 194064
O. Mudrak
Institute of Cytology, Russian Academy of Sciences
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 194064
M. Khodorkovskiy
Peter the Great St. Petersburg Polytechnic University
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 195251
A. Nikiforov
Institute of Cytology, Russian Academy of Sciences; Peter the Great St. Petersburg Polytechnic University
编辑信件的主要联系方式.
Email: andrey.nikiforov@gmail.com
俄罗斯联邦, St. Petersburg, 194064; St. Petersburg, 195251
V. Kulikova
Institute of Cytology, Russian Academy of Sciences; Peter the Great St. Petersburg Polytechnic University
编辑信件的主要联系方式.
Email: veronika.a.kulikova@gmail.com
俄罗斯联邦, St. Petersburg, 194064; St. Petersburg, 195251
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