Email this article Analyzing the Data Bank of Proteins Space Structures (PDB): A Geometrical Approach
- Authors: Vilkul E.A.1, Ivanov A.O.2,3, Mishchenko A.S.4, Popelenskii T.Y.2, Tuzhilin A.A.2, Shaytan K.V.5
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Affiliations:
- Department of Probability Theory, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
- Department of Differential Geometry and Applications, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
- Department of Mathematical Modeling, Bauman Moscow Technical State University
- Department of High Geometry and Topology, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
- Department of Bioengineering, Biological Faculty, Lomonosov Moscow State University
- Issue: Vol 225, No 4 (2017)
- Pages: 555-564
- Section: Article
- URL: https://ogarev-online.ru/1072-3374/article/view/239762
- DOI: https://doi.org/10.1007/s10958-017-3477-2
- ID: 239762
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Abstract
A geometrical approach to the analysis of a data bank containing information on space structures of proteins is suggested. As a result of the analysis, several relationships concerning possible conformations are found, and also there is obtained a list of polypeptides whose structures differ essentially from typical concepts of the 3D-structure of proteins. Those deviations could indicate possible errors and gaps of the interpreting models in use, as well as some new unknown relations and rules.
About the authors
E. A. Vilkul
Department of Probability Theory, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
Author for correspondence.
Email: elena.tuzhilina@mail.ru
Russian Federation, Moscow
A. O. Ivanov
Department of Differential Geometry and Applications, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University; Department of Mathematical Modeling, Bauman Moscow Technical State University
Email: elena.tuzhilina@mail.ru
Russian Federation, Moscow; Moscow
A. S. Mishchenko
Department of High Geometry and Topology, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
Email: elena.tuzhilina@mail.ru
Russian Federation, Moscow
Th. Yu. Popelenskii
Department of Differential Geometry and Applications, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
Email: elena.tuzhilina@mail.ru
Russian Federation, Moscow
A. A. Tuzhilin
Department of Differential Geometry and Applications, Faculty of Mechanics and Mathematics, Lomonosov Moscow State University
Email: elena.tuzhilina@mail.ru
Russian Federation, Moscow
K. V. Shaytan
Department of Bioengineering, Biological Faculty, Lomonosov Moscow State University
Email: elena.tuzhilina@mail.ru
Russian Federation, Moscow
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