Мақаланы E-mail арқылы жіберу Effects of some 5-anilino-1,2,4-thiadiazole derivatives onto leukemic cells
- Авторлар: Orlova M.A.1,2, Trofimova T.P.1,2, Proshin A.N.3, Orlov A.P.1
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Мекемелер:
- Department of Chemistry, M. V. Lomonosov Moscow State University
- Department of Biochemistry and Pharmacology, D. Rogachev Federal Clinical Center of Pediatric Hematology, Oncology and Immunology
- Department of Organic Synthesis, Institute of Physiological Active Compounds of Russian Academy of Sciences
- Шығарылым: Том 66, № 5 (2017)
- Беттер: 932-934
- Бөлім: Brief Communications
- URL: https://ogarev-online.ru/1066-5285/article/view/240654
- DOI: https://doi.org/10.1007/s11172-017-1833-5
- ID: 240654
Дәйексөз келтіру
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Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The antileukemic activities of some thiadiazole derivatives in the forms of hydrochlorides and salicylates have been determined. The insertion of salicylate ion in the compound increases the therapeutic index, mainly due to the reduction of cytotoxicity against healthy cells.
Негізгі сөздер
Авторлар туралы
M. Orlova
Department of Chemistry, M. V. Lomonosov Moscow State University; Department of Biochemistry and Pharmacology, D. Rogachev Federal Clinical Center of Pediatric Hematology, Oncology and Immunology
Хат алмасуға жауапты Автор.
Email: Orlova.radiochim@mail.ru
Ресей, Bld. 3, 1 Leninskie Gory, Moscow, 119992; 1 ul. Samora Mashel, Moscow, 117997
T. Trofimova
Department of Chemistry, M. V. Lomonosov Moscow State University; Department of Biochemistry and Pharmacology, D. Rogachev Federal Clinical Center of Pediatric Hematology, Oncology and Immunology
Email: Orlova.radiochim@mail.ru
Ресей, Bld. 3, 1 Leninskie Gory, Moscow, 119992; 1 ul. Samora Mashel, Moscow, 117997
A. Proshin
Department of Organic Synthesis, Institute of Physiological Active Compounds of Russian Academy of Sciences
Email: Orlova.radiochim@mail.ru
Ресей, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
A. Orlov
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: Orlova.radiochim@mail.ru
Ресей, Bld. 3, 1 Leninskie Gory, Moscow, 119992
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