Hydroxamic acids: synthesis and adjuvant activity in combinatorial anticancer therapy


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

Monoand disubstituted N-hydroxyamides of dicarboxylic acids were prepared by reaction of dicarboxylic acids or acid anhydrides with hydroxylamine. The use of these compounds in combinatorial cytostatic therapy of implanted tumors with cisplatin or cyclophosphamide totally inhibits metastasis formation in B16 melanoma and Lewis lung carcinoma, and resulted in 100% survival of leukemic animals.

作者简介

B. Fedorov

Institute of Problems of Chemical Physics, Russian Academy of Sciences

编辑信件的主要联系方式.
Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

M. Fadeev

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

A. Eremeev

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

N. Konovalova

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

G. Bogdanov

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

L. Tatyanenko

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

T. Sashenkova

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

D. Mishchenko

Institute of Problems of Chemical Physics, Russian Academy of Sciences

Email: boris-45@inbox.ru
俄罗斯联邦, 1 prosp. Akad. N. N. Semenova, Chernogolovka, Moscow Region, 142432

补充文件

附件文件
动作
1. JATS XML

版权所有 © Springer Science+Business Media New York, 2016