Nucleation and Growth Modeling of Protein Crystals in Capillaries

Аннотация

Within this work we model the spatial dependences of protein concentration, nucleation probability and the radius of lysozyme crystal in the experiments on capillary counter-diffusion crystallization. Within the model approach, we evaluate the conditions for the formation of lysozyme crystals with the target separation of 100 µm between centers of protein crystals. The predicted and observed number density, sizes and positions of protein crystals in capillary are in excellent agreement.