THE IMPORTANCE OF INTERLEIKIN-1ß UNDER DIFFERENT FORMS OF HOV-INFECTION

The article presents the results of examination of sampling of patients suffering with different forms of HCV-infection. The level of interleikin-1ß, proinflammatory cytokine, different periods of disease were analyzed and compared with corresponding indicators in healthy donors. It is established that the levels of interleikin-1ß and related clinical biochemical indicators (alanine aminotransferase and aspartate aminotransferase) are increased in blood serum of patients with HCV-infection at the onset of disease and decrease during the progress of disease. The increase of the level of interleikin-1ß in patients with different dynamics of HCV-infection testifies the ineffectiveness of applied counter-relapse therapy. The levels of interleikin-1ß significantly differ depending on of presence of HCV-infection and form of course of infection process. The diagnostic significance of detection of interleikin-1ß in combination with other common methods for prognosis of course of disease is demonstrated.

hepatitis C, cytokine system, interleikin-1ß, HCV-infection