Synthesis and Antiglycation Activity of Novel S-Carboxyalkyl Derivatives of 2-Thiouracil

A. A. Spasov; A. N. Geisman; V. A. Kosolapov; D. A. Babkov; A. I. Rashchenko; V. A. Babkova; O. Yu. Zakhar’yashcheva; A. A. Ozerov

doi:10.1007/s11094-019-02047-3

Synthesis and Antiglycation Activity of Novel S-Carboxyalkyl Derivatives of 2-Thiouracil

作者: Spasov A.A.¹^,2, Geisman A.N.¹^,2, Kosolapov V.A.¹, Babkov D.A.¹, Rashchenko A.I.¹, Babkova V.A.¹, Zakhar’yashcheva O.Y.¹, Ozerov A.A.¹^,2
隶属关系:
1. Volgograd State Medical University
2. Volgograd Medical Science Center
期: 卷 53, 编号 7 (2019)
页面: 610-615
栏目: Article
URL: https://ogarev-online.ru/0091-150X/article/view/245897
DOI: https://doi.org/10.1007/s11094-019-02047-3
ID: 245897

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

S-carboxyalkyl derivatives of 2-thiouracil were synthesized and their pharmacological activity was studied. Several of the compounds were characterized by antiglycation activity. These compounds had no effect on PPAR or glucokinase activity and had weak activity in cleaving protein crosslinks.