Formulation Development and Study of Prolonged Release from Amben Peroral Preparations Based on Hydrophobic Matrices
- 作者: Nifontova G.O.1,2, Dolotova O.V.1, Sarantseva I.V.1, Akhmetzyanova A.R.3, Krechetov S.P.1, Krasnyuk I.I.2
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隶属关系:
- Life Sciences Center, Moscow Institute of Physics and Technology
- Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
- I. M. Sechenov First Moscow State Medical University
- 期: 卷 50, 编号 2 (2016)
- 页面: 90-95
- 栏目: Drug Synthesis Methods and Manufacturing Technology
- URL: https://ogarev-online.ru/0091-150X/article/view/244325
- DOI: https://doi.org/10.1007/s11094-016-1404-3
- ID: 244325
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详细
Results from research on formulation development and prolonged release of peroral 4-aminomethylbenzoic acid (amben) using hydrophobic lipid and polymer matrices are reported. It is shown that the amben release parameters considering its solubility at various pH values can be achieved by using the studied polymer hydrophobic matrices.
作者简介
G. Nifontova
Life Sciences Center, Moscow Institute of Physics and Technology; Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
编辑信件的主要联系方式.
Email: galya.nif@yandex.ru
俄罗斯联邦, Dolgoprudnyi, Moscow Oblast; Khimki, Moscow Oblast, 141402
O. Dolotova
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
俄罗斯联邦, Dolgoprudnyi, Moscow Oblast
I. Sarantseva
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
俄罗斯联邦, Dolgoprudnyi, Moscow Oblast
A. Akhmetzyanova
I. M. Sechenov First Moscow State Medical University
Email: galya.nif@yandex.ru
俄罗斯联邦, Moscow, 119991
S. Krechetov
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
俄罗斯联邦, Dolgoprudnyi, Moscow Oblast
I. Krasnyuk
Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
Email: galya.nif@yandex.ru
俄罗斯联邦, Khimki, Moscow Oblast, 141402
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