Отправить статью по E-mail Synthesis and Pharmacological Activity of Some α-Aminoketone Hydrochlorides
- Авторы: Gevorgyan G.A.1, Gasparyan N.K.1, Papoyan O.A.1, Avakimyan D.A.1, Tatevosyan A.A.1, Panosyan H.A.2
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Учреждения:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
- Molecular Structure Research Center, National Academy of Sciences of Armenia
- Выпуск: Том 51, № 2 (2017)
- Страницы: 107-110
- Раздел: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244512
- DOI: https://doi.org/10.1007/s11094-017-1565-8
- ID: 244512
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Аннотация
New α-bromoethanones were synthesized by bromination of 1-[4(3,4)-substituted phenyl]-2-phenyl[3(4)-substituted phenyl]ethanones and were reacted with various amines in Et2O to produce the corresponding 1-[4-alkoxyphenyl(3-bromophenyl)]-2-phenyl-[3(4)-halophenyl]-2-aminoethanones. It was shown that the synthesized compounds possessed moderate antibacterial and pronounced peripheral n-cholinolytic activity.
Об авторах
G. Gevorgyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Автор, ответственный за переписку.
Email: gyulgev@gmail.com
Армения, 26 Prosp. Azatutyan, Yerevan, 0014
N. Gasparyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Армения, 26 Prosp. Azatutyan, Yerevan, 0014
O. Papoyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Армения, 26 Prosp. Azatutyan, Yerevan, 0014
D. Avakimyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Армения, 26 Prosp. Azatutyan, Yerevan, 0014
A. Tatevosyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Армения, 26 Prosp. Azatutyan, Yerevan, 0014
H. Panosyan
Molecular Structure Research Center, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Армения, 26 Prosp. Azatutyan, Yerevan, 0014
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