Enviar artigo por via de e-mail Synthesis and Pharmacological Activity of Some α-Aminoketone Hydrochlorides
- Autores: Gevorgyan G.A.1, Gasparyan N.K.1, Papoyan O.A.1, Avakimyan D.A.1, Tatevosyan A.A.1, Panosyan H.A.2
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Afiliações:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
- Molecular Structure Research Center, National Academy of Sciences of Armenia
- Edição: Volume 51, Nº 2 (2017)
- Páginas: 107-110
- Seção: Article
- URL: https://ogarev-online.ru/0091-150X/article/view/244512
- DOI: https://doi.org/10.1007/s11094-017-1565-8
- ID: 244512
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Resumo
New α-bromoethanones were synthesized by bromination of 1-[4(3,4)-substituted phenyl]-2-phenyl[3(4)-substituted phenyl]ethanones and were reacted with various amines in Et2O to produce the corresponding 1-[4-alkoxyphenyl(3-bromophenyl)]-2-phenyl-[3(4)-halophenyl]-2-aminoethanones. It was shown that the synthesized compounds possessed moderate antibacterial and pronounced peripheral n-cholinolytic activity.
Sobre autores
G. Gevorgyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Autor responsável pela correspondência
Email: gyulgev@gmail.com
Armênia, 26 Prosp. Azatutyan, Yerevan, 0014
N. Gasparyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Armênia, 26 Prosp. Azatutyan, Yerevan, 0014
O. Papoyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Armênia, 26 Prosp. Azatutyan, Yerevan, 0014
D. Avakimyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Armênia, 26 Prosp. Azatutyan, Yerevan, 0014
A. Tatevosyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Armênia, 26 Prosp. Azatutyan, Yerevan, 0014
H. Panosyan
Molecular Structure Research Center, National Academy of Sciences of Armenia
Email: gyulgev@gmail.com
Armênia, 26 Prosp. Azatutyan, Yerevan, 0014
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