Local Anesthetic Activity of a Promising Piperidine Derivative (LAS-54) in Combination with Epinephrine

G. M. Pichkhadze; G. S. Smagulova; D. M. Kadyrova; K. D. Praliev; V. K. Yu

doi:10.1007/s11094-016-1498-7

Local Anesthetic Activity of a Promising Piperidine Derivative (LAS-54) in Combination with Epinephrine

Авторлар: Pichkhadze G.M.¹, Smagulova G.S.¹, Kadyrova D.M.¹, Praliev K.D.², Yu V.K.²
Мекемелер:
1. S. D. Asfendiyarov Kazakh National Medical University
2. A. B. Bekturov Institute of Chemical Sciences, Ministry of Education and Science of the Republic of Kazakhstan
Шығарылым: Том 50, № 9 (2016)
Беттер: 600-602
Бөлім: Article
URL: https://ogarev-online.ru/0091-150X/article/view/244445
DOI: https://doi.org/10.1007/s11094-016-1498-7
ID: 244445

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Статистика

Аннотация

Results from studies of the local anesthetic activity of LAS-54 [4-(benzoyloxy)-3-butoxypiperidinium chloride] (synthesized at the Laboratory of the Chemistry of Synthetic and Natural Drugs, Bekturov Institute of Chemical Sciences) in combination with epinephrine are presented. It was found that joint application of the vasoconstrictor with LAS-54, especially at low concentrations, prolonged infiltration, conduction, and spinal anesthesia.

Негізгі сөздер

conduction, infiltration, and spinal anesthesia, piperidine, vasoconstrictor, epinephrine