Email this article Using a Molecular Sensor Array with Colorimetric Detection to Identify Active Ingredients in Drug Formulations
- Authors: Chaplenko A.A.1, Monogarova O.V.1, Oskolok K.V.1
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Affiliations:
- Department of Chemistry, M. V. Lomonosov Moscow State University
- Issue: Vol 53, No 4 (2019)
- Pages: 347-352
- Section: Structure of Chemical Compounds, Methods of Analysis and Process Control
- URL: https://ogarev-online.ru/0091-150X/article/view/245760
- DOI: https://doi.org/10.1007/s11094-019-02004-0
- ID: 245760
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Abstract
A method for multiplex digital colorimetric qualitative analysis of nonsteroidal anti-inflammatory drugs (meloxicam, acetylsalicylic acid and its metabolites, paracetamol), β-adrenoblockers (carvedilol), secretolytics (bromhexine), fluoroquinolones (ofloxacin), metabolic stimulants (meldonium dihydrate), etc., was developed. The molecular chip operating efficiency was confirmed by verifying the authenticity of >40 medicinal substances. The proposed universal approach was new in principle and could be used for pharmaceutical quality control.
About the authors
A. A. Chaplenko
Department of Chemistry, M. V. Lomonosov Moscow State University
Author for correspondence.
Email: a.a.chaplenko@yandex.ru
Russian Federation, 1/3 Leninskie Gory, Moscow, 119991
O. V. Monogarova
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: a.a.chaplenko@yandex.ru
Russian Federation, 1/3 Leninskie Gory, Moscow, 119991
K. V. Oskolok
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: a.a.chaplenko@yandex.ru
Russian Federation, 1/3 Leninskie Gory, Moscow, 119991
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