Using a Molecular Sensor Array with Colorimetric Detection to Identify Active Ingredients in Drug Formulations


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A method for multiplex digital colorimetric qualitative analysis of nonsteroidal anti-inflammatory drugs (meloxicam, acetylsalicylic acid and its metabolites, paracetamol), β-adrenoblockers (carvedilol), secretolytics (bromhexine), fluoroquinolones (ofloxacin), metabolic stimulants (meldonium dihydrate), etc., was developed. The molecular chip operating efficiency was confirmed by verifying the authenticity of >40 medicinal substances. The proposed universal approach was new in principle and could be used for pharmaceutical quality control.

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A. Chaplenko

Department of Chemistry, M. V. Lomonosov Moscow State University

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Email: a.a.chaplenko@yandex.ru
俄罗斯联邦, 1/3 Leninskie Gory, Moscow, 119991

O. Monogarova

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: a.a.chaplenko@yandex.ru
俄罗斯联邦, 1/3 Leninskie Gory, Moscow, 119991

K. Oskolok

Department of Chemistry, M. V. Lomonosov Moscow State University

Email: a.a.chaplenko@yandex.ru
俄罗斯联邦, 1/3 Leninskie Gory, Moscow, 119991

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