Pulsed Dendritic Cells for the Therapy of Experimental Glioma
- 作者: Chekhonin I.V.1, Gurina O.I.1, Cherepanov S.A.2, Abakumov M.A.2, Ionova K.P.1, Zhigarev D.K.1, Makarov A.V.1, Chekhonin V.P.1,2
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隶属关系:
- V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
- Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
- 期: 卷 161, 编号 6 (2016)
- 页面: 792-796
- 栏目: Microbiology and Immunology
- URL: https://ogarev-online.ru/0007-4888/article/view/237786
- DOI: https://doi.org/10.1007/s10517-016-3512-1
- ID: 237786
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详细
We obtained the morphologically, cytofluorometrically, and functionally mature dendritic cells from rats that were pulsed with antigens of the C6 glioma tissue extract. The concentrations of angiogenesis antigens (VEGF, VEGFR-1, and VEGFR-2) and periglioma zone proteins (GFAP, connexin 43, and BSAT1) in the pulsing extract were measured by ELISA. Our results drove us to a conclusion that despite mature phenotype of pulsed dendritic cell, the antigenic composition of glioma tissue extracts should be modified.
作者简介
I. Chekhonin
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
O. Gurina
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
S. Cherepanov
Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
M. Abakumov
Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
K. Ionova
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
D. Zhigarev
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
A. Makarov
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow
V. Chekhonin
V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Ministry of Health of the Russian Federation; Department of Medical Nanobiotechnologies, Medical Biological Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation
Email: ivan-chekhonin@yandex.ru
俄罗斯联邦, Moscow; Moscow
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