Отправить статью по E-mail The response of the mononuclear phagocyte system to chronic hyperglycemia
- Авторы: Bulavintseva T.S.1,2, Danilova I.G.1,2,3, Briliant S.A.1,2,3, Smirnyh S.E.1,2, Abidov M.T.4
-
Учреждения:
- Ural Federal University named after the first President of Russia B.N. Yeltsin
- Institute of Immunology and Physiology, Ural Branch
- Institute of Medical Cell Technologies
- Institute of Immunopathology
- Выпуск: Том 61, № 6 (2016)
- Страницы: 919-922
- Раздел: Cell Biophysics
- URL: https://ogarev-online.ru/0006-3509/article/view/152159
- DOI: https://doi.org/10.1134/S0006350916050031
- ID: 152159
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
In this study we revealed a common reaction of cells of the mononuclear phagocyte system in the central and peripheral immunopoietic organs and pancreas in rats with chronic hyperglycemia. The activation of monocytopoiesis and recruitment of mononuclear phagocytes in peripheral tissues were observed. The modulation of the functional activity of mononuclear phagocytes by 3-aminophthal-hydrazide contributed to the normalization of monocytopoietic intensity and a decrease in the level of macrophagal infiltration in the thymus, pancreas, and peripancreatic lymph nodes. These changes indicate that mononuclear phagocytes are involved in the adaptive response to chronic hyperglycemia.
Ключевые слова
Об авторах
T. Bulavintseva
Ural Federal University named after the first President of Russia B.N. Yeltsin; Institute of Immunology and Physiology, Ural Branch
Автор, ответственный за переписку.
Email: omella@yandex.ru
Россия, ul. Mira 19, Yekaterinburg, 620002; ul. Pervomaiskaya 106, Yekaterinburg, 620049
I. Danilova
Ural Federal University named after the first President of Russia B.N. Yeltsin; Institute of Immunology and Physiology, Ural Branch; Institute of Medical Cell Technologies
Email: omella@yandex.ru
Россия, ul. Mira 19, Yekaterinburg, 620002; ul. Pervomaiskaya 106, Yekaterinburg, 620049; ul. K. Marksa 22a, Yekaterinburg, 620026
S. Briliant
Ural Federal University named after the first President of Russia B.N. Yeltsin; Institute of Immunology and Physiology, Ural Branch; Institute of Medical Cell Technologies
Email: omella@yandex.ru
Россия, ul. Mira 19, Yekaterinburg, 620002; ul. Pervomaiskaya 106, Yekaterinburg, 620049; ul. K. Marksa 22a, Yekaterinburg, 620026
S. Smirnyh
Ural Federal University named after the first President of Russia B.N. Yeltsin; Institute of Immunology and Physiology, Ural Branch
Email: omella@yandex.ru
Россия, ul. Mira 19, Yekaterinburg, 620002; ul. Pervomaiskaya 106, Yekaterinburg, 620049
M. Abidov
Institute of Immunopathology
Email: omella@yandex.ru
Россия, ul. Molodogvardeiskaya 57/1, Moscow, 121351
Дополнительные файлы
