Enviar artigo por via de e-mail Characterization of an Acellular Dermal Matrix Obtained by Different Detergent-Enzymatic Methods
- Autores: Sarbaeva N.N.1, Milyakova M.N.1, Rossinskaya V.V.1, Gribkova O.V.1, Dolgushkin D.A.1
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Afiliações:
- Samara State Medical University, Ministry of Health of the Russian Federation
- Edição: Volume 51, Nº 3 (2017)
- Páginas: 166-169
- Seção: Article
- URL: https://ogarev-online.ru/0006-3398/article/view/235030
- DOI: https://doi.org/10.1007/s10527-017-9707-6
- ID: 235030
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Resumo
Acellular dermal matrixes (ADM) for reconstructive surgery were made by treating skin samples from rats and humans with sodium dodecylsulfate (SDS), sodium deoxycholate (DOC), saponin, and DNase. A mixture of SDS and DOC removed cell residues effectively, though the ADM had cytotoxic properties. After treatment with 2% DOC, there was no cytotoxic effect and the resulting material contained 27-202 ng/mg dry weight DNA and from 0.07 to 2.6% fat, depending on the source of the samples.
Sobre autores
N. Sarbaeva
Samara State Medical University, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: sarbaeva@gmail.com
Rússia, Samara
M. Milyakova
Samara State Medical University, Ministry of Health of the Russian Federation
Email: sarbaeva@gmail.com
Rússia, Samara
V. Rossinskaya
Samara State Medical University, Ministry of Health of the Russian Federation
Email: sarbaeva@gmail.com
Rússia, Samara
O. Gribkova
Samara State Medical University, Ministry of Health of the Russian Federation
Email: sarbaeva@gmail.com
Rússia, Samara
D. Dolgushkin
Samara State Medical University, Ministry of Health of the Russian Federation
Email: sarbaeva@gmail.com
Rússia, Samara
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