Electrical Stimulation of Human Connective Tissue Cells on Layers of Composite Structures with a Nanocarbon Framework
- Авторы: Mezentseva M.V.1, Russu L.I.1, Privalova P.Y.2, Gerasimenko A.Y.2,3, Zhurbina N.N.2, Petukhov V.A.2, Pyankov E.S.2, Ichkitidze L.P.2,3, Suetina I.A.1
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Учреждения:
- Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
- National Research University of Electronic Technology (MIET)
- I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
- Выпуск: Том 52, № 5 (2019)
- Страницы: 301-304
- Раздел: Article
- URL: https://ogarev-online.ru/0006-3398/article/view/235776
- DOI: https://doi.org/10.1007/s10527-019-09835-x
- ID: 235776
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Аннотация
A technique for electrical stimulation of growth of connective tissue cells on composite structures with a nanocarbon framework was developed. Cells were stimulated with pulsed electric signal (amplitude, 200 mV; pulse duration, 2.5 ms) for 5 h. A study of the effect of the electrical stimulation on the viability of cells showed an increase in the proliferative activity and in the density of cells adhering to the surface of composite structure layers. The aspect ratio for the cell structure subjected to the electrical stimulation was 1.4 times greater than for nonstimulated cells. The developed technique can be used in tissue engineering, an important branch of regenerative medicine.
Об авторах
M. Mezentseva
Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
Email: gerasimenko@bms.zone
Россия, Moscow
L. Russu
Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
Email: gerasimenko@bms.zone
Россия, Moscow
P. Privalova
National Research University of Electronic Technology (MIET)
Email: gerasimenko@bms.zone
Россия, Zelenograd, Moscow
A. Gerasimenko
National Research University of Electronic Technology (MIET); I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: gerasimenko@bms.zone
Россия, Zelenograd, Moscow; Moscow
N. Zhurbina
National Research University of Electronic Technology (MIET)
Email: gerasimenko@bms.zone
Россия, Zelenograd, Moscow
V. Petukhov
National Research University of Electronic Technology (MIET)
Email: gerasimenko@bms.zone
Россия, Zelenograd, Moscow
E. Pyankov
National Research University of Electronic Technology (MIET)
Email: gerasimenko@bms.zone
Россия, Zelenograd, Moscow
L. Ichkitidze
National Research University of Electronic Technology (MIET); I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: gerasimenko@bms.zone
Россия, Zelenograd, Moscow; Moscow
I. Suetina
Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya
Email: gerasimenko@bms.zone
Россия, Moscow
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