COVID-19 in Russia: Epidemiology and Molecular Genetic Monitoring
- 作者: Akimkin V.G.1, Semenenko T.A.2, Ugleva S.V.1, Dubodelov D.V.1, Kuzin S.N.1, Yacyshina S.B.1, Khafizov K.F.1, Petrov V.V.1, Cherkashina A.S.1, Gasanov G.A.1, Svanadze N.K.1
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隶属关系:
- Central Research Institute of Epidemiology
- National Research Center of Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya
- 期: 卷 77, 编号 4 (2022)
- 页面: 254-260
- 栏目: INFECTIOUS DISEASES: CURRENT ISSUES
- URL: https://ogarev-online.ru/vramn/article/view/125585
- DOI: https://doi.org/10.15690/vramn2121
- ID: 125585
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Background. The COVID-19 pandemic has exposed health problems, but at the same time has become a powerful impetus for the development of new scientific research in the field of epidemiology, clinic of infectious diseases, diagnostics, bioinformatics and digital methods. On the basis of the Central Research Institute of Epidemiology of Rospotrebnadzor, new unique test systems for the detection of SARS-CoV-2 RNA based on real-time PCR based on loop isothermal amplification (IT) technology have been developed, which allows you to examine samples 3–4 times faster than those developed previously. The Central Research Institute of Epidemiology of Rospotrebnadzor has developed and put into operation the Russian Platform for Aggregation of Information on Virus Genomes (VGARus). The VGARus database contains information about the nucleotide sequences of the SARS-CoV-2 viruses and their mutations, and the SOLAR Integration Platform has been created to quickly transfer the results of PCR studies to all interested citizens of the Russian Federation.
Aims – to study the manifestations of the epidemic process of COVID-19 and the prevalence of genovariants of the SARS-CoV-2 virus in the Russian Federation.
Methods. A retrospective epidemiological analysis of the incidence of COVID-19 was carried out from March 30, 2020 to May 17, 2022 in the Russian Federation. The database was formed on the basis of the materials of the Rospotrebnadzor report form No. 970 “Information on cases of infectious diseases in persons with suspected new coronavirus infection”, data from the WHO, the domestic information portal Stopkoronavirus.rf and the Yandex DataLens data visualization and analysis service were used, information on SARS-CoV-2 genovariants in the VGARus database.
Results. When analyzing the manifestations of the COVID-19 epidemic process in the Russian Federation for 2020–2022. Two stages have been identified. The first stage was characterized by the rapid spread of the SARS-CoV-2 virus from megacities to other regions of the country and the use of non-specific prevention measures. The beginning of the second was due to the evolution of the SARS-CoV-2 virus and a change in its biological properties, followed by a change in the prevailing genovariants on the territory of the Russian Federation.
Conclusion. As a result of the study, it was found that with each subsequent increase in the incidence of COVID-19, there was a decrease in the severity of the course and the proportion of pneumonia in the structure of the clinical forms of the disease.
作者简介
Vasily Akimkin
Central Research Institute of Epidemiology
Email: vgakimkin@yandex.ru
ORCID iD: 0000-0003-4228-9044
SPIN 代码: 4038-7455
MD, PhD, Professor, Academician of the RAS
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowTatiana Semenenko
National Research Center of Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya
Email: meddy@inbox.ru
ORCID iD: 0000-0002-6686-9011
SPIN 代码: 8375-2270
MD, PhD, Professor
俄罗斯联邦, MoscowSvetlana Ugleva
Central Research Institute of Epidemiology
编辑信件的主要联系方式.
Email: uglevas@bk.ru
ORCID iD: 0000-0002-1322-0155
SPIN 代码: 8840-5814
MD, PhD, Associate Professor
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowDmitry Dubodelov
Central Research Institute of Epidemiology
Email: dubodelov@cmd.su
ORCID iD: 0000-0003-3093-5731
SPIN 代码: 4860-7909
MD, PhD
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowStanislav Kuzin
Central Research Institute of Epidemiology
Email: kuzin@cmd.su
ORCID iD: 0000-0002-0616-9777
SPIN 代码: 1372-7623
MD, PhD, Professor
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowSvetlana Yacyshina
Central Research Institute of Epidemiology
Email: svetlana.yatsyshina@pcr.ms
ORCID iD: 0000-0003-4737-941X
SPIN 代码: 7156-2948
PhD in Biology, Senior Research Associate
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowKamil Khafizov
Central Research Institute of Epidemiology
Email: khafizov@cmd.su
ORCID iD: 0000-0001-5524-0296
SPIN 代码: 9082-5749
PhD in Biology
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowVadim Petrov
Central Research Institute of Epidemiology
Email: petrov@pcr.ms
ORCID iD: 0000-0002-3503-2366
SPIN 代码: 9852-8292
head of the scientific group for the development of new molecular biological technologies
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowAnna Cherkashina
Central Research Institute of Epidemiology
Email: cherkashina@pcr.ms
ORCID iD: 0000-0001-7970-7495
SPIN 代码: 7854-7358
PhD in Chemistry
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowGasan Gasanov
Central Research Institute of Epidemiology
Email: gasanovgt500@gmail.com
ORCID iD: 0000-0002-0121-521X
SPIN 代码: 9726-9380
post-graduate student
俄罗斯联邦, 3a, Novogireevskaya str., 111123, MoscowNino Svanadze
Central Research Institute of Epidemiology
Email: svanadze@cmd.su
ORCID iD: 0000-0001-7524-3080
SPIN 代码: 2345-4460
Epidemiologist, Laboratory of viral hepatitis, Department of molecular diagnostics and epidemiology
俄罗斯联邦, 3a, Novogireevskaya str., 111123, Moscow参考
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