Email this article The effectiveness of different regimens of testosterone gel therapy in men with androgen deficiency
- Authors: Kuzmenko A.V.1, Gyaurgiev T.A.1, Bakutina Y.Y.1, Zarubayco A.Y.1
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Affiliations:
- N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation
- Issue: Vol 10, No 1 (2020)
- Pages: 57-60
- Section: Original articles
- URL: https://ogarev-online.ru/uroved/article/view/25806
- DOI: https://doi.org/10.17816/uroved10157-60
- ID: 25806
Cite item
Abstract
The results of androgen replacement therapy with the appointment of a transdermal gel with testosterone in patients with androgen deficiency were presented. 90 men with testosterone deficiency (<12 nmol/L) and impaired erectile function were observed. The average age of patients was 58 ± 5.2 years. Patients were divided into 3 groups. Patients of the 1st (control) group underwent basic behavioral therapy, the 2nd group received basic therapy with testosterone gel for a dose of 50 mg, the 3rd group received basic therapy with testosterone gel at a dose of 100 mg. The duration of treatment was 6 months. The use of testosterone in the form of a transdermal gel led to a significant increase in the content of total testosterone in both patients of the 2nd (50 mg) and 3rd groups (100 mg). A dose-dependent effect was noted, in patients of the 3rd group the level of testosterone was significantly higher than in patients 2nd group. An increase in testosterone was accompanied by a decrease in FSH and LH levels.
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##article.viewOnOriginalSite##About the authors
Andrey V. Kuzmenko
N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: kuzmenkoav09@yandex.ru
Doctor of Medical Science, Professor, Head, Department of Urology
Russian Federation, VoronezhTimur A. Gyaurgiev
N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation
Email: tima001100@mail.ru
Candidate of Medical Science, Associate Professor, Department of Urology
Russian Federation, VoronezhYulia Yu. Bakutina
N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation
Email: yul.bakutina@yandex.ru
Student
Russian Federation, VoronezhAlena Yu. Zarubayco
N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of the Russian Federation
Email: alenazarubaiko@yandex.ru
Student
Russian Federation, VoronezhReferences
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