Modern anti-IgE therapies in children with chronic spontaneous urticaria: clinical cases
- Authors: Larkova I.A.1, Revyakina V.A.1
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Affiliations:
- The Federal Research Center for Nutrition, Вiotechnology and Food Safety
- Issue: Vol 17, No 4 (2020)
- Pages: 85-89
- Section: Case reports
- URL: https://ogarev-online.ru/raj/article/view/121631
- DOI: https://doi.org/10.36691/RJA1392
- ID: 121631
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Abstract
The diagnostics and treatment of chronic urticaria is still a pressing problem for specialists of different profiles. Despite the fact that the first line drugs for urticaria treatment are non-sedating H1- antihistamines, there are a number of patients who do not respond to these medications even in their increased doses. This article presents clinical cases of anti-IgE-therapy efficacy in children suffering from urticaria and angioedema.
CONCLUSION: The clinical cases demonstrate current possibilities of successful and safe anti-IgE-therapy of various clinical manifestations of chronic spontaneous urticaria and angioedema in children.
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##article.viewOnOriginalSite##About the authors
Inna A. Larkova
The Federal Research Center for Nutrition, Вiotechnology and Food Safety
Author for correspondence.
Email: inna_larkova@mail.ru
ORCID iD: 0000-0001-7640-0754
Senior researcher of Allergy Department, MD
Russian Federation, MoscowVera A. Revyakina
The Federal Research Center for Nutrition, Вiotechnology and Food Safety
Email: 5356797@mail.ru
ORCID iD: 0000-0002-1149-7927
Head of Allergy Department
Russian Federation, MoscowReferences
- Клиническая аллергология детского возраста с неотложными состояниями / под ред. Балаболкина И.И., Булгаковой В.А. М. : МИА, 2011.
- Российская Ассоциация Аллергологов и Клинических Иммунологов. Федеральные клинические рекомендации по диагностике и лечению крапивницы. М., 2018.
- Zuberbier T., Aberer W., Asero R., et al. The EAACI/GA²LEN/ EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria // Allergy. 2018. Vol. 73. N 7. P. 1393–1414. doi: 10.1111/all.13397
- Horn MP, Pachlopnik JM, Vogel M, et al. Conditional autoimmunity mediated by human natural anti-Fc(epsilon)RIalpha autoantibodies? // FASEB J. 2001. N 12. P. 2268–2274.doi: 10.1096/fj.00-0890hyp
- Beck L.A., Bernstein J.A., Maurer M. A review of international recommendations for the diagnosis and management of chronic urticaria // Acta Derm Venereol. 2017. Vol. 97. N 2. P. 149–158. doi: 10.2340/00015555-2496
- Maurer М., Rosen K., Hsieh H.J., et al. Оmalizumab for the treatment of chronic idiopathic or spontaneous urticaria // N Engl J Med. 2013. Vol. 368. N 10. P. 924–935.doi: 10.1056/NEJMoa1215372
- Rosen K., Maurer M., Hsieh H., et al. Response to: ‘Omalizumab for the treatment of chronic idiopathic or spontaneous urticaria: a critical appraisal’ // Br J Dermatol. 2014. N 1. P. 15–16. doi: 10.1111/bjd.13075
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