Amniotic fluid is a marker of the condition of the fetus. Is it so?
- Authors: Bezhenar V.F.1, Ivanova L.A.2, Ivanov D.O.3, Krasnogorskaya O.L.3
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Affiliations:
- Academisian I.P. Pavlov First St. Petersburg State Medical University
- Kirov Military Medical Academy
- St. Petersburg State Pediatric Medical University
- Issue: Vol 13, No 6 (2022)
- Pages: 5-16
- Section: Editorial
- URL: https://ogarev-online.ru/pediatr/article/view/133036
- DOI: https://doi.org/10.17816/PED1365-16
- ID: 133036
Cite item
Abstract
BACKGROUND: In the presence of meconium in the amniotic fluid, childbirth is usually classified as a high-risk group, which leads to an expansion of indications for operative delivery. Also in the literature there are indications of an increase in the frequency of the birth of a child in a state of asphyxia, with premature rupture of amniotic fluid.
AIM: The aim of this study is to determine the significance of the influence of meconium color of amniotic fluid and the duration of the anhydrous period on the birth of a child in a state of asphyxia.
MATERIALS AND METHODS: A retrospective study was conducted between the two groups in 12,342 women delivered at the Perinatal Center of the Pediatric University.
RESULTS: Meconium coloration of amniotic fluid was 2 times more common in the presence of hypoxia, and 5 times more common in the presence of severe fetal hypoxia during full-term pregnancy, while in premature pregnancy, the child was born in a state of asphyxia, regardless of the color of the amniotic fluid. Premature rupture of amniotic fluid occurred at the birth of a full-term baby in a state of asphyxia statistically significantly more often, although the duration of the anhydrous period did not have statistically significant differences in the groups.
CONCLUSIONS: Premature rupture of amniotic fluid at the birth of a premature baby had no differences in the groups with and without asphyxia, however, the duration of the anhydrous period was statistically significantly longer in patients who gave birth to children in a state of asphyxia. With an anhydrous interval of 26 hours or more, the risk of having a child in a state of moderate and severe asphyxia increased. The risk of ascending infection of the placenta of the third stage during preterm labor increased with an anhydrous interval of more than 53 minutes, which confirms the feasibility of prescribing antibiotic therapy for premature rupture of amniotic fluid during preterm pregnancy at the time of diagnosis of this condition, regardless of the planned obstetric tactics.
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##article.viewOnOriginalSite##About the authors
Vitaly F. Bezhenar
Academisian I.P. Pavlov First St. Petersburg State Medical University
Email: lida.ivanova@gmail.com
MD, PhD, Dr. Sci. (Med.), Professor, Head, Department of Obstetrics, Gynecology and Reproductology
Russian Federation, Saint PetersburgLidiia A. Ivanova
Kirov Military Medical Academy
Author for correspondence.
Email: lida.ivanova@gmail.com
MD, PhD, Assistant Professor, Department of Obstetrics and Gynecology
Russian Federation, Saint PetersburgDmitry O. Ivanov
St. Petersburg State Pediatric Medical University
Email: doivanov@yandex.ru
MD, PhD, Dr. Sci. (Med.), Professor, Chief Freelance Neonatologist of the Ministry of Health of Russia, Rector, Head of the Department of Neonatology with courses of Neurology and Obstetrics and Gynecology
Russian Federation, Saint PetersburgOlga L. Krasnogorskaya
St. Petersburg State Pediatric Medical University
Email: krasnogorskaya@yandex.ru
MD, PhD, Assistant Professor, Department of Pathological Anatomy at the rate of Forensic Medicine, Head of Autopsy Department SPbGPMU Clinic
Russian Federation, Saint PetersburgReferences
- Ashurova NG, Tosheva II, Kudratova D. Sostoyaniye gotovnosti rodovykh putei u rozhenits s dorodovym razryvom plodnykh obolochek. Reproduktivnaya Meditsina. 2018;(2(35)):32–34. (In Russ.)
- Bekchanova BB. Current state of the problem of premature outline of nutritive waters in obstetrics in pregnant women. Avitsenna. 2020;(69):7–9. (In Russ.)
- Ikhtiyarova GA, Tosheva II, Aslonova MZh. Induction of labor in women with antenatal death of fetus with rupture of membranes and intrauterine infection. Infektsiya, immunitet i farmakologiya. 2019;5:254. (In Russ.)
- Keda LN, Liskovich VA, Ganchar YeP, Zverko VL. Algoritm vedeniya prezhdevremennykh rodov pri prezhdevremennom izlitii okoloplodnykh vod. Reproductive Health. Eastern Europe. 2011;(6(18)):4–10. (In Russ.)
- Prezhdevremennye rody. Klinicheskie rekomendatsii Ministerstva zdravookhraneniya Rossiiskoi Federatsii. 2020. 42 p. (In Russ.)
- Kuznetsova EE. Rannyaya diagnostika vnutriutrobnoi infektsii i profilaktika ee oslozhnenii pri prezhdevremennom izlitii okoloplodnykh vod [dissertation abstract]. Moscow. 2014. 24 p. (In Russ.)
- Nikolayeva MG, Serdyuk GV, Grigor’yeva EE. Role of gene polymorfism of plasminogen activator ingibitor type I as a risk factor for premature rupture of membrane at term pregnancy. Bulletin of Siberian Medicine. 2013;12(6):43–47. (In Russ.)
- Orlova VS, Kalashnikova IV, Naberezhnev YuI. Podkhody k vedeniyu nedonoshennoi beremennosti pri prezhdevremennom izlitii okoloplodnykh vod. Nauchnye vedomosti Belgorodskogo Gosudarstvennogo Universiteta. Seriya: Meditsina. Farmatsiya. 2010;(16(87)):13–22. (In Russ.)
- Serov VN, Degtyarev DN, Shmakov RG, et al. Prezhdevremennyi razryv plodnykh obolochek (prezhdevremennoe izlitie vod). Obstetrics and Gynecology. 2015;(S5):14–32. (In Russ.)
- Rakhmatullayeva MM. Treatment of bacterial vaginosis in early of pregnancy. Farmateka. 2017;(12):67–68. (In Russ.)
- Reanimatsiya i stabilizatsiya novorozhdennykh detei v rodil’nom zale: Metodicheskoe pis’mo / Baibarina EN, editor. Moscow; 2020. 55 p. (In Russ.)
- Tosheva II, Ashurova NG. Results of rupture of membranes in preterm during pregnancy. Journal Bulletin of the Dagestan State Medical Academy. 2019;(4(33)): 34–37. (In Russ.)
- Walsh MC, Fanaroff JM. Meconium stained fluid: approach to the mother and the baby. Clin Perinatol. 2007;34(4):653–665. doi: 10.1016/j.clp.2007.10.005
- Williams JW. Obstetrics: A Textbook for Use of Students & Practitioners. 1903. 845 p.
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