Thrombosis risks of permanent vascular access

Aim. To identify the factors affecting the occurrence of thrombosis of permanent vascular access and to determine their significance.

Materials and Methods. The results of treatment of 168 patients with native arteriovenous radio-cephalic fistula were analyzed. The results of treatment were traced within 1 year. According to the results of treatment, patients were divided into 2 groups: the 1^st group – patients who did not develop thrombosis of the arteriovenous fistula within 1 year of hemodialysis, and the 2^nd group – patients with a dysfunction of permanent vascular access developed due to thrombosis within the first year.

Results. On the basis of the obtained data, the risk factors for thrombosis of permanent vascular access within 6 months were: repeated operations, duration of anticoagulant therapy, correction of anticoagulant therapy, antibiotic therapy. Risk factors for thrombosis of the PVA for the period from 6 months to 12 months were: atherosclerosis, fistula vein diameter, repeated operations, the number of repeated operations, a reason for a repeated operation, duration of anticoagulant therapy, correction of anticoagulant therapy, antibiotic therapy.

Conclusions. The results of the study suggest that the realization of the identified risk factors is not the only cause of complications. For a more detailed consideration of the probability for thrombosis of permanent vascular access in different time intervals, it seems appropriate to use multidimensional mathematical modeling.