Ventilation-perfusion relationships in smokers

Abstract

To assess the effect of smoking on ventilation-perfusion relations in 62 smokers and 30 non-smokers aged 20 to 57 years old we used mass spectrometry to determine partial pressure of O₂ and CO₂ in alveolar air (pАО₂ and рАСО₂) and growth rate of рСО₂ in alveolar exhalation phase (ΔpACO₂/tA).
To exclude heart and lung diseases, in addition to the general clinical examination, we studied GEL, SPR1 and Wotchal-Tiffno index. These indices in the healthy and smoking groups were within normal limits and did not differ significantly, although they were slightly decreased in smokers.

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