Defects of the bone base of the skeleton and the possibility of their elimination using biologically based methods

Abstract

To close the flaw in the musculoskeletal system, the Dutchman Nehren used an animal bone back in 1668, thereby opening one of the most interesting chapters of reconstructive surgery. The use of one's own bone for this purpose is associated with the names of Mckiven, Lexer, Albi, and already in the XVII century, its transplantation brought up to 50% successful outcomes. However, only in the 40s of the XX century, bone transplantation began to be performed more widely, tissue banks appeared, and immunologists began to study the antigenic properties of bone, which should have further expanded the possibilities of reconstructive surgery.

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