Clinicomyographic characteristic of the pathology of neurotrophic regulation of skeletal muscles

The clinical, electromyographic and mechanomyographic examinations of patients with diseases of central and peripheric nervous systems and the experimental myographic and morphohistochemical investigations of various models of impulsive and unimpulsive neurotrophic effect disorders on mice’ muscles arc performed. Based on the clinicoexperimen- tal comparisons the conclusions are drawn regarding the importance of mechanomyography in the diagnosis of neuromuscular system state, in the development of estimation methods of the course and efficacy of therapeutic and rehabilitation measures in neurogenetic lesions of muscles.