Features of the diphtheria clinic in children fully vaccinated with diphtheria toxoid

Although the lighter course of diphtheria in vaccinated patients, compared with unvaccinated ones, is generally recognized, however, there are two opinions regarding the comparative characteristics of the acute period of diphtheria in those vaccinated with diphtheria toxoid and unvaccinated ones. Some believe that active immunization does not have any effect on the duration of the first (acute) period and, consequently, the cleansing of the pharynx from raids, the improvement of the general condition occurs in the same time as in unvaccinated (E. M. Borok, N. A. Nikitina, N. I. Nisevich). Others note that in the actively immunized, the acute period proceeds more favorably: the raids go down faster, the general condition improves earlier than in the unvaccinated, and the one-sidedness of the tonsils is more often observed in the picture of the throat (A.D. Levasheva, V. N. Azbelev, N. P. Kudryavtseva, N. K. Belaya, V. L. Olshevskaya, E. M. Dmitrieva-Ravikovich, S. N. Rozanov). At the same time, in a larger number of cases, there is a discrepancy between the severity of the general condition and the amount of plaque (with severe intoxication, the raids are limited, localized).