Intracutaneous reaction as a new method in the diagnosis of malaria

Since the causative agent of malaria is known to us and the clinical picture of this disease is sometimes extremely characteristic, it would seem that there is nothing easier than making an appropriate diagnosis. However, it must be admitted that difficulties and even mistakes occur very often in this case, and when the disease is acute, and even more so when it has a chronic course. If plasmodia are found in the blood, then, of course, any question disappears. It is known, however, that even in an acute and subacute state, when the disease is usually accompanied by characteristic temperature curves with chills and then after a strictly defined time, sometimes plasmodia in the blood cannot be found even with repeated studies in a thick drop.