The use of nibufin for fractures of tubular bones
- Authors: Bogdanovich U.Y.1, Bakhtiozin F.S.1, Prokhorov V.P.1
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Affiliations:
- Kazan Institute of Traumatology and Orthopedics
- Issue: Vol 50, No 2 (1969)
- Pages: 49-50
- Section: Theoretical and clinical medicine
- URL: https://ogarev-online.ru/kazanmedj/article/view/79836
- DOI: https://doi.org/10.17816/kazmj79836
- ID: 79836
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Abstract
Nibufin, a paranitrophenyl ester of dibutylphosphinic acid, was synthesized at the Laboratory of Organic Chemistry. A.E. Arbuzov KHTI A.I. Razumov and O.A.Mukhacheva (1957). The drug was pharmacologically examined and proposed for practical use by IV Zaikonnikova (1961). As her studies have shown, nibufin has a pronounced anticholinesterase property, increases the tone of smooth muscle organs - the intestines, uterus, and enhances peristalsis. Compared with other organophosphorus compounds used in medicine - armin, phosphacol, phosarbin, it is much less toxic.
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##article.viewOnOriginalSite##About the authors
U. Ya. Bogdanovich
Kazan Institute of Traumatology and Orthopedics
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Kazan
F. Sh. Bakhtiozin
Kazan Institute of Traumatology and Orthopedics
Email: info@eco-vector.com
Russian Federation, Kazan
V. P. Prokhorov
Kazan Institute of Traumatology and Orthopedics
Email: info@eco-vector.com
Russian Federation, Kazan
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