The question of syphilis without chancre

Feldman discusses chancre-free syphilis. (Syphilis d'emblée) (Clinical medicine, 1928, vol. VI, No. 5). The dogma that syphilis necessarily begins with chancre has recently been greatly shaken by both experimental and clinical observations. Kolle experiments on rabbit "pullers" proved the possibility of a syphilitic hematogenous infection without chancre: rabbits infected with syphilis, which did not reveal any clinical phenomena of syphilis when inoculating their organs to other rabbits, turned out to be sick with syphilis. A number of clinical observations (the author has collected in the world literature 8 reliable, irreproachable cases, of which one of his own also confirms the possibility of syphilis without chancre. who, as it turned out later, suffered from chronic syphilis (Syphilis ingnoratah) (Donnar did not undergo Wasserm reaction before the operation.) 74 days after the blood transfusion, the patient who received the blood transfusion is diagnosed with fresh syphilis: roseola, swelling lymphatic glands, positive WR. Careful searches for the primary affect - chancre were unsuccessful. all the time in the hospital under strict medical supervision. The described case is, i.e. arr. an undoubted manifestation of hematogenous syphilitic infection without chancre. The author makes a reservation that he means syphilis without a clinical chancre, but not without a histological one, since, of course, no one can prove or deny the presence of the latter, that is, microscopic syphiloma without visible clinical phenomena. The article contains all the literature on this extremely complex and interesting issue.