On the synergism of adrenaline and thyroidin

Abstract

The question of the synergism and antagonism of the action of drugs is one of the most interesting and important from the point of view of general pharmacology - the more so because it arises in most cases and in the study of the pharmacodynamics of individual drugs. As regards in particular drugs acting in the same direction, it is not yet possible to summarize all the possibilities and to give exhaustive explanations as to what circumstances and how the effect is enhanced in each individual case. In the literature on this subject we find only attempts to establish whether there is summation of doses or activation. In some cases the question is raised of the activation of one substance by another, and of the creation of more favorable conditions by one drug for the development of the pharmacological action by the other.

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