Therapeutic Uses of Normal Immunoglobulin for Pulmonary Diseases

In the complex treatment of 30 patients with severe pulmonary diseases (males — 14, females — 16; age — from 15 to 70 years), we used normal immunoglobulin for intravenous administration, developed at the Kirov Research Institute of Blood Transfusion. In 20 patients the process was bilateral, in 10 it was unilateral. The sclerotic form of chronic pneumonia according to the classification of KG Nikulin (stage I) was established in 7 patients, bronchiectasis (stage II) in 11 and abscessing (stage III) in 12. The patients stayed in the hospital from 21 to 89 days. Immunoglobulin was injected intravenously (the rate of administration was no more than 20 drops per minute), 50–75 ml 2 times a week in a total dose of 100–150 ml. The drug was prescribed only for extensive lung lesions, bronchiectasis, abscess formation; in 2 patients it was used in preparing them for lung operations during critical periods of the course of the disease. Under the influence of complex treatment with the use of immunoglobulin for intravenous administration, patients showed positive shifts in the indicators of total protein, protein fractions and albumin-globulin index (see table).