The importance of tissue and vascular factors in the mechanism of hemostasis in childbirth

The role of tissue and vascular factors in the mechanism of hemostasis during labor was studied in 68 women with various types of obstetric pathology. A significant decrease in the coagulation activity of tissue and vascular factors was found in women in labor before the onset of subsequent and early postpartum hemorrhages and in women in labor with antenatal fetal death compared with healthy women. The processes of thrombus formation in the uterus during labor are activated by tissue and vascular factors of hemostasis to such an extent that they proceed extremely quickly and during the subsequent period provide a final, reliable hemostasis.