Clinical tolerance of single doses of ethionamide in patients with pulmonary tuberculosis
- Authors: Smirnov G.A.1, Zamaletdinova L.T.1, Mikhailovskaya V.A.1, Latypova S.I.1
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Affiliations:
- Kazan GIDUV them. V. I. Lenin
- Issue: Vol 63, No 4 (1982)
- Pages: 61-63
- Section: Articles
- URL: https://ogarev-online.ru/kazanmedj/article/view/62312
- DOI: https://doi.org/10.17816/kazmj62312
- ID: 62312
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Abstract
The tolerance of ethionamide was studied in 851 patients with pulmonary tuberculosis. The drug was administered at 0.75 g at a time. Side effects were noted in 31% of individuals, and complete intolerance - in 6.6%. For the rest, adverse reactions disappeared after a short break in taking the drug or when it was administered at night. In a number of patients, to remove side effects, it was necessary to reduce a single dose of ethionamide to 0.5 g or give it 0.25 g three times. More often, side complications occurred in persons with chronic diseases of the gastrointestinal tract, as well as in elderly and senile patients.
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##article.viewOnOriginalSite##About the authors
G. A. Smirnov
Kazan GIDUV them. V. I. Lenin
Author for correspondence.
Email: info@eco-vector.com
Russian Federation
L. T. Zamaletdinova
Kazan GIDUV them. V. I. Lenin
Email: info@eco-vector.com
Russian Federation
V. A. Mikhailovskaya
Kazan GIDUV them. V. I. Lenin
Email: info@eco-vector.com
Russian Federation
S. I. Latypova
Kazan GIDUV them. V. I. Lenin
Email: info@eco-vector.com
Russian Federation
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